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A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.

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A comprehensive guide for both fundamentals and real-world applications of environmental engineering Written by noted experts, Handbook of Environmental Engineering offers a comprehensive guide to environmental engineers who desire to contribute to mitigating problems, such as flooding, caused by extreme weather events, protecting populations in coastal areas threatened by rising sea levels, reducing illnesses caused by polluted air, soil, and water from improperly regulated industrial and transportation activities, promoting the safety of the food supply. Contributors not only cover such timely environmental topics related to soils, water, and air, minimizing pollution created by industrial plants and processes, and managing wastewater, hazardous, solid, and other industrial wastes, but also treat such vital topics as porous pavement design, aerosol measurements, noise pollution control, and industrial waste auditing. This important handbook: Enables environmental engineers to treat problems in systematic ways Discusses climate issues in ways useful for environmental engineers Covers up-to-date measurement techniques important in environmental engineering Reviews current developments in environmental law for environmental engineers Includes information on water quality and wastewater engineering Informs environmental engineers about methods of dealing with industrial and municipal waste, including hazardous waste Designed for use by practitioners, students, and researchers, Handbook of Environmental Engineering contains the most recent information to enable a clear understanding of major environmental issues.

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A comprehensive resource that draws a balance between theory and applications of nonlinear time series analysis Nonlinear Time Series Analysis offers an important guide to both parametric and nonparametric methods, nonlinear state-space models, and Bayesian as well as classical approaches to nonlinear time series analysis. The authors—noted experts in the field—explore the advantages and limitations of the nonlinear models and methods and review the improvements upon linear time series models. The need for this book is based on the recent developments in nonlinear time series analysis, statistical learning, dynamic systems and advanced computational methods. Parametric and nonparametric methods and nonlinear and non-Gaussian state space models provide a much wider range of tools for time series analysis. In addition, advances in computing and data collection have made available large data sets and high-frequency data. These new data make it not only feasible, but also necessary to take into consideration the nonlinearity embedded in most real-world time series. This vital guide: • Offers research developed by leading scholars of time series analysis • Presents R commands making it possible to reproduce all the analyses included in the text • Contains real-world examples throughout the book • Recommends exercises to test understanding of material presented • Includes an instructor solutions manual and companion website Written for students, researchers, and practitioners who are interested in exploring nonlinearity in time series, Nonlinear Time Series Analysis offers a comprehensive text that explores the advantages and limitations of the nonlinear models and methods and demonstrates the improvements upon linear time series models.

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An essential guide to the basic concepts that comprise the study of sociology with contributions from an international range of leading experts Core Concepts in Sociology is a comprehensive guide to the essential concepts relevant to the current study of the discipline and wider social science. The contributing authors cover a wide range of concepts that remain at the heart of sociology including those from its academic founding and others much more recent in their development. The text contains contributions from an international panel of leading figures in the field, utilizing their expertise on core concepts and presenting an accessible introduction for students. Drawing on the widest range of ideas, research, current literature and expert assessment, Core Concepts in Sociology contains over 90 concepts that represent the discipline. Coverage includes concepts ranging from aging to capitalism, democracy to economic sociology, epistemology to everyday life, media to risk, stigma and much more. This vital resource: Sets out the concepts that underpin the study of sociology and wider social science Contains contributions from an international panel of leading figures in the field Includes a comprehensive review of the basic concepts that comprise the foundation and essential development of the discipline Designed as a concise and accessible resource Written for students, researchers and wider professionals with an interest in the field of sociology, Core Concepts in Sociology offers a concise, affordable and accessible resource for studying the underpinnings of sociology and social science.

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Bovine surgery is both challenging and complicated. Not only does the surgeon have to decide whether surgery is economically justified, but surgery often has to be performed in a sub-optimal environment. Following on from the worldwide success of the first edition, this new edition continues to act as a step-by-step guide to standard surgical techniques. Now with two new authors from Switzerland and North America, both the text and illustrations have been considerably expanded. In addition, special attention is given to issues relating to peri-operative analgesia and animal welfare, food safety, and drug dosages. Maintains the popular concise and accessible format of the first edition – perfect for on-the-field work; Two additional authors, with world renowned expertise in bovine surgery and lameness; Detailed instruction on the basics of effective surgery – proper instrumentation, asepsis, effective anaesthesia and essential techniques; Much more information on lameness, as well as numerous new line drawings to aid instruction.

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Covers the latest aquarium gadgets Design a dazzling underwater environment with this bestselling guide! Setting up your first freshwater aquarium can be a daunting task. This friendly guide answers all your questions, from setting up your tank and selecting fish to the water, chemicals, plants, and much more. There's also expanded guidance on combining different species of fish, maintaining a tank, cleaning gravel, and dealing with common problems such as algae. Discover how to * Choose the right aquarium * Select the best fish * Get good deals on equipment * Maintain a clean, healthy environment * Handle tank pitfalls * Breed your fish

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The updated edition of the essential guide to environmental psychology Thoroughly revised and updated, the second edition, Environmental Psychology: An Introduction offers an overview of the interplay between humans and their environments. The text examines the influence of the environment on human experiences, behaviour and well-being and explores the factors influencing environmental behaviour, and ways to encourage pro-environmental behaviour. The revised edition is a state-of-the art review of relevant theories and research on each of these topics. With contributions from an international panel of noted experts, the text addresses a wealth of topics including the main research methods in environmental psychology; effects of environmental stress; emotional impacts and meanings of natural environment experience; aesthetic appraisals of architecture; how to measure environmental behaviour; cognitive, emotional and social factors explaining environmental behaviour; effects and acceptability of strategies to promote pro-environmental factors; and much more. This important book: Discusses the environmental factors that threaten and promote human wellbeing Explores a wide range of factors influencing actions that affect environmental conditions Discusses the effects and acceptability of approaches that aim to encourage pro-environmental behavior Presents research results conducted in different regions in the world Contains contributions from noted experts Written for scholars and practitioners in the field, the revised edition of Environmental Psychology offers a comprehensive review of the most recent research available in environmental psychology.

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Students at universities the world over will benefit from the authors' concise treatment, arising out of lectures given for a graduate and advanced undergraduate course at Penn State University (USA) and University of Technology Delft (NL). The textbook begins by addressing, in general terms, the phenomena and peculiarities that occur at the nanoscale. In the following five chapters, readers are introduced in detail to nanoscale physics, chemistry, materials science, and biology, followed by chapters on synthesis and fabrication as well as characterization at the nanoscale. In the next four chapters a variety of exemplary applications taken from a wide range of sectors are also presented and discussed. Concerns for safety, environmental impact, workforce development, economic wellbeing, and societal change issues arising from nanotechnology are woven throughout the book and additionally form the focus of the last two chapters.

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This is the latest volume in the IOC Encyclopaedia of Sports Medicine series, summarizing the evidence from all relevant sources on the genetic and molecular basis of sports and other human physical performance. The initial chapters address the basic science of genomics and genetics and the regulation of gene expression. Additional chapters provide authoritative information on the genetics of complex performance phenotypes, the contributions of small animal research, family and twin studies, and ethnic comparisons. A final section addresses the issue of the contribution of specific genes and molecular markers as related to endurance, strength and power, and responsiveness to specific conditioning programs. This latest volume in the Encyclopaedia of Sports Medicine Series from the Medical Commission of the International Olympic Committee is a must for sports and exercise scientists who require a thorough guide to the most cutting edge science in this expanding field.

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This comprehensive new volume in the Encyclopaedia of Sports Medicine series, published under the auspices of the International Olympic Committee, delivers an up-to-date, state of the art presentation of the medical conditions that athletes may suffer from during training and competition. Presented in a clear style and format, The Olympic Textbook of Medicine in Sport, covers not only the basic approach to training, monitoring training and the clinical implications of excessive training, but also deals with all the major systems in the body, and focuses on medical conditions that athletes may suffer from in each system. Medical conditions in athletes with disabilities, genetics and exercise and emergency sports medicine are also uniquely examined. The Olympic Textbook of Medicine in Sport draws on the expertise of an international collection of contributors who are recognized as leaders in their respective fields. The systematic approach followed in the book will make it invaluable to all medical doctors and other health personnel who serve athletes and sports teams. Sports practitioners are provided with a clinical approach to the prevention, diagnosis and treatment of common and less common medical problems encountered by athletes. This volume should be kept close at hand for frequent consultation.

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