LITMIR.BIZ

As the impacts of anthropogenic activities increase in both magnitude and extent, biodiversity is coming under increasing pressure. Scientists and policy makers are frequently hampered by a lack of information on biological systems, particularly information relating to long-term trends. Such information is crucial to developing an understanding as to how biodiversity may respond to global environmental change. Knowledge gaps make it very difficult to develop effective policies and legislation to reduce and reverse biodiversity loss. This book explores the gap between global commitments to biodiversity conservation, and local action to track biodiversity change and implement conservation action. High profile international political commitments to improve biodiversity conservation, such as the targets set by the Convention on Biological Diversity, require innovative and rapid responses from both science and policy. This multi-disciplinary perspective highlights barriers to conservation and offers novel solutions to evaluating trends in biodiversity at multiple scales.

Подробнее

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.

Подробнее

Mixed modelling is very useful, and easier than you think! Mixed modelling is now well established as a powerful approach to statistical data analysis. It is based on the recognition of random-effect terms in statistical models, leading to inferences and estimates that have much wider applicability and are more realistic than those otherwise obtained. Introduction to Mixed Modelling leads the reader into mixed modelling as a natural extension of two more familiar methods, regression analysis and analysis of variance. It provides practical guidance combined with a clear explanation of the underlying concepts. Like the first edition, this new edition shows diverse applications of mixed models, provides guidance on the identification of random-effect terms, and explains how to obtain and interpret best linear unbiased predictors (BLUPs). It also introduces several important new topics, including the following: Use of the software SAS, in addition to GenStat and R. Meta-analysis and the multiple testing problem. The Bayesian interpretation of mixed models. Including numerous practical exercises with solutions, this book provides an ideal introduction to mixed modelling for final year undergraduate students, postgraduate students and professional researchers. It will appeal to readers from a wide range of scientific disciplines including statistics, biology, bioinformatics, medicine, agriculture, engineering, economics, archaeology and geography. Praise for the first edition: “One of the main strengths of the text is the bridge it provides between traditional analysis of variance and regression models and the more recently developed class of mixed models…Each chapter is well-motivated by at least one carefully chosen example…demonstrating the broad applicability of mixed models in many different disciplines…most readers will likely learn something new, and those previously unfamiliar with mixed models will obtain a solid foundation on this topic.”—Kerrie Nelson University of South Carolina, in American Statistician, 2007

Подробнее

Religion (and spirituality) is very much alive and shapes the cultural values and aspirations of psychiatrist and patient alike, as does the choice of not identifying with a particular faith. Patients bring their beliefs and convictions into the doctor-patient relationship. The challenge for mental health professionals, whatever their own world view, is to develop and refine their vocabularies such that they truly understand what is communicated to them by their patients. Religion and Psychiatry provides psychiatrists with a framework for this understanding and highlights the importance of religion and spirituality in mental well-being. This book aims to inform and explain, as well as to be thought provoking and even controversial. Patiently and thoroughly, the authors consider why and how, when and where religion (and spirituality) are at stake in the life of psychiatric patients. The interface between psychiatry and religion is explored at different levels, varying from daily clinical practice to conceptual fieldwork. The book covers phenomenology, epidemiology, research data, explanatory models and theories. It also reviews the development of DSM V and its awareness of the importance of religion and spirituality in mental health. What can religious traditions learn from each other to assist the patient? Religion and Psychiatry discusses this, as well as the neurological basis of religious experiences. It describes training programmes that successfully incorporate aspects of religion and demonstrates how different religious and spiritual traditions can be brought together to improve psychiatric training and daily practice. Describes the relationship of the main world religions with psychiatry Considers training, policy and service delivery Provides powerful support for more effective partnerships between psychiatry and religion in day to day clinical care This is the first time that so many psychiatrists, psychologists and theologians from all parts of the world and from so many different religious and spiritual backgrounds have worked together to produce a book like this one. In that sense, it truly is a World Psychiatric Association publication. Religion and Psychiatry is recommended reading for residents in psychiatry, postgraduates in theology, psychology and psychology of religion, researchers in psychiatric epidemiology and trans-cultural psychiatry, as well as professionals in theology, psychiatry and psychology of religion

Подробнее

From Santa, elves and Ebenezer Scrooge, to the culture wars and virgin birth, Christmas – Philosophy for Everyone explores a host of philosophical issues raised by the practices and beliefs surrounding Christmas. Offers thoughtful and humorous philosophical insights into the most widely celebrated holiday in the Western world Contributions come from a wide range of disciplines, including philosophy, theology, religious studies, English literature, cognitive science and moral psychology The essays cover a wide range of Christmas themes, from a defence of the miracle of the virgin birth to the relevance of Christmas to atheists and pagans

Подробнее

The Organizational Network Fieldbook «This is the ultimate resource for practitioners who want to implement insights from organizational network analysis and thinking. Dozens of concrete examples, interventions, and practical advice from network experts show you what you can do to strengthen networks and boost performance. This book is essential for anyone in business, government, or consulting who wants to get network thinking from analysis to action in organizations.» —WAYNE BAKER, professor of management and organizations, Stephen M. Ross School of Business, University of Michigan «What a great idea this book is! The Organizational Network Fieldbook will demand to be read by anyone undertaking any social network efforts in their organization. It is not only a unique book, but it is also very well thought-out, finely written, and exceptionally pragmatic. It's a great achievement for the authors and a great boon to all practitioners.» —LARRY PRUSAK, researcher and consultant, and the founder and former director of the Institute for Knowledge Management In this practical companion to the best-selling Driving Results Through Social Networks, the authors draw on their network-building activities in organizations such as ConocoPhillips, 3M, and the United States Department of Defense in order to provide a compilation of highly practical approaches to help leaders shift their focus from formal organizational structures to a better understanding of flexible networks.

Подробнее

Tunnel engineering is one of the oldest, most interesting but also challenging engineering disciplines and demands not only theoretical knowledge but also practical experience in geology, geomechanics, structural design, concrete construction, machine technology, construction process technology and construction management. The two-volume «Handbuch des Tunnel- und Stollenbaus» has been the standard reference work for German-speaking tunnellers in theory and practice for 30 years. The new English edition is based on a revised and adapted version of the third German edition and reflects the latest state of knowledge. The book is published in two volumes, with the second volume covering both theoretical themes like design basics, geological engineering, structural design of tunnels and monitoring instrumentation, and also the practical side of work on the construction site such as dewatering, waterproofing and scheduling as well as questions of tendering, award and contracts, data management and process controlling. As with volume I, all chapters include practical examples.

Подробнее

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

Подробнее

Ob es um Tinte, Farben, Genussmittel, Zundholzer, Pharmazeutika oder gar den Stein der Weisen geht: Chemie und Kulturgeschichte sind nicht voneinander zu trennen. Besonders anschaulich wird das, wenn chemische Experimente in historischem Ambiente vorgefuhrt werden. Zwischen Rheinsberg in Brandenburg und Tettnang am Bodensee finden in Schlossern, Museen und Klostern die Experimentalvortrage statt, auf denen aufbauend dieses Buch entstand. Nun in der zweiten Auflage, sind weitere Experimente dazugekommen, die sich zum Beispiel mit Silber und Gold, Tod und Teufel beschaftigen. Die Dichte der historischen Standorte auf der Deutschlandkarte nimmt zu: vom Bergbau im Harz bis «Doktor Faustus» im Kloster Maulbronn.

Подробнее

“This book will be a valuable resource for psychologists and educators who work with children or adolescents who are having difficulties with memory and learning. Translating theory and research into practice is a talent that Dr. Dehn possesses and we will benefit from his professional skills.” – From the Foreword by Daniel C. Miller, PhD, ABPP, ABSNP, NCSP An indispensable guide that examines the effect of long-term memory functions on children's learning Long-Term Memory Problems in Children and Adolescents: Assessment, Intervention, and Effective Instruction is the first book of its kind for psychologists, school psychologists, and special education teachers who need an overview of long-term memory as it relates to learning and education. It presents the best practices for assessing long-term memory functions, as well as selecting and using evidence-based instructional practices with memory-impaired students. This useful and timely guide bridges theory and practice to provide professional guidance with coverage of: Risk factors that can lead to long-term memory impairments How long-term memory relates to other types of memory The subcomponents and processes of long-term memory and how they relate to academic achievement What is known about the neuroanatomy of how memories are formed The developmental trajectory of memory and learning Common types of memory dysfunction Memory assessment strategies, interventions for memory problems, and instructional practices that support memory Author Milton Dehn draws on his extensive experience as a trainer and workshop presenter, school psychologist, and educator to present both the theory and research on long-term memory in children and adolescents in this book. Specific step-by-step guidance and hands-on case studies enable professionals to identify how memory can be assessed as well as the interventions that can be linked to the results of the assessment.

Подробнее