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This book provides a comprehensive and accessible source of information on all types of sweeteners and functional ingredients, enabling manufacturers to produce low sugar versions of all types of foods that not only taste and perform as well as sugar-based products, but also offer consumer benefits such as calorie reduction, dental health benefits, digestive health benefits and improvements in long term disease risk through strategies such as dietary glycaemic control. Now in a revised and updated new edition which contains seven new chapters, part I of this volume addresses relevant digestive and dental health issues as well as nutritional considerations. Part II covers non-nutritive, high-potency sweeteners and, in addition to established sweeteners, includes information to meet the growing interest in naturally occurring sweeteners. Part III deals with the bulk sweeteners which have now been used in foods for over 20 years and are well established both in food products and in the minds of consumers. In addition to the «traditional» polyol bulk sweeteners, newer products such as isomaltulose are discussed. These are seen to offer many of the advantages of polyols (for example regarding dental heath and low glycaemic response) without the laxative side effects if consumed in large quantity. Part IV provides information on the sweeteners which do not fit into the above groups but which nevertheless may offer interesting sweetening opportunities to the product developer. Finally, Part V examines bulking agents and multifunctional ingredients which can be beneficially used in combination with all types of sweeteners and sugars.

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A well-written, hands-on, single-source guide to the professional practice of civil engineering There is a growing understanding that to be competitive at an international level, civil engineers not only must build on their traditional strengths in technology and science but also must acquire greater mastery of the business of civil engineering. Project management, teamwork, ethics, leadership, and communication have been defined as essential to the successful practice of civil engineering by the ASCE in the 2008 landmark publication, Civil Engineering Body of Knowledge for the 21st Century (BOK2). This single-source guide is the first to take the practical skills defined by the ASCE BOK2 and provide illuminating techniques, quotes, case examples, problems, and information to assist the reader in addressing the many challenges facing civil engineers in the real world. Civil Engineer's Handbook of Professional Practice: Focuses on the business and management aspects of a civil engineer's job, providing students and practitioners with sound business management principles Addresses contemporary issues such as permitting, globalization, sustainability, and emerging technologies Offers proven methods for balancing speed, quality, and price with contracting and legal issues in a client-oriented profession Includes guidance on juggling career goals, life outside work, compensation, and growth From the challenge of sustainability to the rigors of problem recognition and solving, this book is an essential tool for those practicing civil engineering.

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Adopting a unique approach, this novel textbook integrates science and business for an inside view on the biotech industry. Peering behind the scenes, it provides a thorough analysis of the foundations of the present day industry for students and professionals alike: its history, its tools and processes, its markets and products. The authors, themselves close witnesses of the emergence of modern biotechnology from its very beginnings in the 1980s, clearly separate facts from fiction, looking behind the exaggerated claims made by start-up companies trying to attract investors. Essential reading for every student and junior researcher looking for a career in the biotech sector.

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A comprehensive guide to sludge management, reuse, and disposal When wastewater is treated, reducing organic material to carbon dioxide, water, and bacterial cells—the cells are disposed of, producing a semisolid and nutrient-rich byproduct called sludge. The expansion in global population and industrial activity has turned the production of excess sludge into an international environmental challenge, with the ultimate disposal of excess sludge now one of the most expensive problems faced by wastewater facilities. Written by two leading environmental engineers, Biological Sludge Minimization and Biomaterials/Bioenergy Recovery Technologies offers a comprehensive look at cutting-edge techniques for reducing sludge production, converting sludge into a value-added material, recovering useful resources from sludge, and sludge incineration. Reflecting the impact of new stringent environmental legislation, this book offers a frank appraisal of how sludge can be realistically managed, covering key concerns and the latest tools: Fundamentals of biological processes for wastewater treatment, wastewater microbiology, and microbial metabolism, essential to understanding how sludge is produced Prediction of primary sludge and waste-activated sludge production, among the chief design and operational challenges of a wastewater treatment plant Technologies for sludge reduction, with a focus on reducing microbial growth yield as well as enhancing sludge disintegration The use of anerobic digestion of sewage sludge for biogas recovery, in terms of process fundamentals, design, and operation The use of the microbial fuel cell (MFC) system for the sustainable treatment of organic wastes and electrical energy recovery

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This second edition is based on the successful concept of the first edition in presenting a unified perspective on molecular charge and energy transfer processes. The authors bridge the regimes of coherent and dissipative dynamics, thus establishing the connection between classic rate theories and modern treatments of ultrafast phenomena. The book serves as an introduction for graduate students and researchers. Among the new topics of this second edition are – semiclassical and quantum-classical hybrid formulations of molecular dynamics – the basics of femtosecond nonlinear spectroscopy – electron transfer through molecular bridges and proteins – multidimensional tunneling in proton transfer reactions – two-exciton states and exciton annihilation in biological and nonbiological chromophore complexes More illustrating examples as well as an enlarged reference list are added. A new chapter gives an introduction into the theory of laser pulse control of molecular transfer processes.

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The mind and the body, when working in harmony, is a fantastic system capable of extraordinary things. With an applied, interactive, and highly visual approach, Fundamentals of Anatomy and Physiology for Student Nurses provides students with an exciting and straightforward understanding of anatomy and physiology, enabling them to deliver high quality care in any setting. This book covers the structure and functions of the human body, with clinical applications throughout. Key features: A clear, straightforward book on anatomy and physiology for all students in nursing and allied health. Fully interactive, with an activity section at the end of each chapter, featuring multiple choice questions, diagram labelling, test your learning questions, crosswords, and 'find out more'. Generous, full colour illustrations throughout Clinical considerations and scenarios throughout showing how the material can be applied to daily practice A companion website where you'll find further exercises, illustrations, and interactive MCQs www.wiley.com/go/peate

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Develops the theory of jet single-time Lagrange geometry and presents modern-day applications Jet Single-Time Lagrange Geometry and Its Applications guides readers through the advantages of jet single-time Lagrange geometry for geometrical modeling. With comprehensive chapters that outline topics ranging in complexity from basic to advanced, the book explores current and emerging applications across a broad range of fields, including mathematics, theoretical and atmospheric physics, economics, and theoretical biology. The authors begin by presenting basic theoretical concepts that serve as the foundation for understanding how and why the discussed theory works. Subusequent chapters compare the geometrical and physical aspects of jet relativistic time-dependent Lagrange geometry to the classical time-dependent Lagrange geometry. A collection of jet geometrical objects are also examined such as d-tensors, relativistic time-dependent semisprays, harmonic curves, and nonlinear connections. Numerous applications, including the gravitational theory developed by both the Berwald-Moór metric and the Chernov metric, are also presented. Throughout the book, the authors offer numerous examples that illustrate how the theory is put into practice, and they also present numerous applications in which the solutions of first-order ordinary differential equation systems are regarded as harmonic curves on 1-jet spaces. In addition, numerous opportunities are provided for readers to gain skill in applying jet single-time Lagrange geometry to solve a wide range of problems. Extensively classroom-tested to ensure an accessible presentation, Jet Single-Time Lagrange Geometry and Its Applications is an excellent book for courses on differential geometry, relativity theory, and mathematical models at the graduate level. The book also serves as an excellent reference for researchers, professionals, and academics in physics, biology, mathematics, and economics who would like to learn more about model-providing geometric structures.

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Practical Manual of Echocardiography in the Urgent Setting covers the essentials of echocardiography in the acute setting, from ultrasound basics to descriptions of all pertinent echocardiographic views to clear stepwise advice on basic calculations and normal/abnormal ranges. This compact new reference: • Provides step-by-step guidance to acquiring the correct views and making the necessary calculations to accurately diagnose cardiac conditions commonly encountered in urgent settings. • Presents information organized by complaint/initial presentation so that readers can work from this first knowledge of the patient through the steps required to pinpoint a diagnosis. • Covers echo basics, from sound wave characteristics/properties to common device settings to basic ultrasound formulas. • Includes diagnostic algorithms fitted to address the differential diagnosis in the most commonly-encountered clinical scenarios. Designed and written by frontline clinicians with extensive experience treating patients, Practical Manual of Echocardiography in the Urgent Setting is the perfect pocket-sized guide for residents in cardiology, emergency medicine, and hospital medicine; trainees in echocardiography; medical students on cardiology or emergency medicine rotations; technicians, nurses, attending physicians – anyone who practices in the urgent setting and who needs reliable guidance on echocardiographic views, data and normal/abnormal ranges to aid rapid diagnosis and decision-making at the point of care.

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The publication of the second edition of this manual comes at an important juncture in the history of clinical research. As advances in information technology make it possible to link individuals and groups in diverse locations in jointly seeking the answers to pressing global health problems, it is critically important to remain vigilant about moral and ethical safeguards for every patient enrolled in a trial. Those who study this manual will be well aware of how to ensure patient safety along with fiscal responsibility, trial efficiency, and research integrity. —Robert Harrington, Professor of Medicine, Director, Duke Clinical Research Institute, Durham, North Carolina, USA The Duke Clinical Research Institute (DCRI) is one of the world's leading academic clinical research organizations; its mission is to develop and share knowledge that improves the care of patients around the world through innovative clinical research. This concise handbook provides a practical «nuts and bolts» approach to the process of conducting clinical trials, identifying methods and techniques that can be replicated at other institutions and medical practices. Designed for investigators, research coordinators, CRO personnel, students, and others who have a desire to learn about clinical trials, this manual begins with an overview of the historical framework of clinical research, and leads the reader through a discussion of safety concerns and resulting regulations. Topics include Good Clinical Practice, informed consent, management of subject safety and data, as well as monitoring and reporting adverse events. Updated to reflect recent regulatory and clinical developments, the manual reviews the conduct of clinical trials research in an increasingly global context. This new edition has been further expanded to include: In-depth information on conducting clinical trials of medical devices and biologics The role and responsibilities of Institutional Review Boards, and Recent developments regarding subject privacy concerns and regulations. Ethical documents such as the Belmont Report and the Declaration of Helsinki are reviewed in relation to all aspects of clinical research, with a discussion of how researchers should apply the principles outlined in these important documents. This graphically appealing and eminently readable manual also provides sample forms and worksheets to facilitate data management and regulatory record retention; these can be modified and adapted for use at investigative sites.

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Practical Osseous Surgery in Periodontics and Implant Dentistry is a step-by-step manual that guides readers through osseous surgery procedures for treating periodontal issues as well as for ensuring proper anchorage of dental implants. Dibart and Dibart use hundreds of color photographs and succinct text to illustrate and explain the most recent advances and techniques for creating the ideal bone structure for each patient. This book covers periodontal therapies including resective surgery, and regenerative surgery, as well as implant therapies, including socket perseveration, correcting bony deficiencies, bone grafts, minimally invasive surgical procedures, and the latest technologies such as Piezosurgery. It also devotes chapters to growth-factor enhanced bone grafts, PiezocisionTM, and restoration of the placed implant. Practical Osseous Surgery in Periodontics and Implant Dentistry focuses on clinical applications of surgical procedures, making it an essential tool for both specialists and generalists with an interest in implant dentistry and osseous surgery procedures.

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