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Urban policy makers are increasingly striving to strengthen the economic competitiveness of their cities. Currently, they do that mainly in the field of the creative knowledge economy – arts, media, entertainment, creative business services, architecture, publishing, design; and ICT, R&D, finance, and law. This book is about the policies that help to realise such objectives: policies driven by classic location theory, cluster policies, ‘creative class’ policies aimed at attracting talent, as well as policies that connect to pathways, place and personal networks. The experiences and policy strategies of 13 city-regions across Europe have been investigated: Amsterdam, Barcelona, Birmingham, Budapest, Dublin, Helsinki, Leipzig, Milan, Munich, Poznan, Riga, Sofia and Toulouse. All have different histories and roles: capital cities and secondary cities; cities with different economies and industries; port-based cities and land-locked cities. And all 13 have different cultural, political and welfare state traditions. Through this wide set of contexts, Place-making and Policies for Competitive Citiescontributes to the debate about the development of creative knowledge cities, their economic growth and competitiveness and advocates the development of context-sensitive tailored approaches. Chapter authors from the 13 European cities rigorously evaluate, reformulate and test assumptions behind old and new policies. This solidly-grounded and policy-focused study on the urban policy of place-making highlights practices for different contexts in managing knowledge-intensive cities and, by drawing on the varied experiences from across Europe, it establishes the state-of-the-art for both academic and policy debates in a fast-moving field.

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This unique treatment systematically interprets a spectrum of importance measures to provide a comprehensive overview of their applications in the areas of reliability, network, risk, mathematical programming, and optimization. Investigating the precise relationships among various importance measures, it describes how they are modelled and combined with other design tools to allow users to solve readily many real-world, large-scale decision-making problems. Presenting the state-of-the-art in network analysis, multistate systems, and application in modern systems, this book offers a clear and complete introduction to the topic. Through describing the reliability importance and the fundamentals, it covers advanced topics such as signature of coherent systems, multi-linear functions, and new interpretation of the mathematical programming problems. Key highlights: Generalizes the concepts behind importance measures (such as sensitivity and perturbation analysis, uncertainty analysis, mathematical programming, network designs), enabling readers to address large-scale problems within various fields effectively Covers a large range of importance measures, including those in binary coherent systems, binary monotone systems, multistate systems, continuum systems, repairable systems, as well as importance measures of pairs and groups of components Demonstrates numerical and practical applications of importance measures and the related methodologies, including risk analysis in nuclear power plants, cloud computing, software reliability and more Provides thorough comparisons, examples and case studies on relations of different importance measures, with conclusive results based on the authors’ own research Describes reliability design such as redundancy allocation, system upgrading and component assignment. This book will benefit researchers and practitioners interested in systems design, reliability, risk and optimization, statistics, maintenance, prognostics and operations. Readers can develop feasible approaches to solving various open-ended problems in their research and practical work. Software developers, IT analysts and reliability and safety engineers in nuclear, telecommunications, offshore and civil industries will also find the book useful.

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An unprecedented look into the present and future of next generation networks, services, and management in the telecommunications industry The telecommunications industry has advanced in rapid, significant, and unpredictable ways into the twenty-first century. Next Generation Telecommunications Networks, Services, and Management guides the global industry and academia even further by providing an in-depth look at current and developing trends, as well as examining the complex issues of developing, introducing, and managing cutting-edge telecommunications technologies. This is an orchestrated set of original chapters written expressly for this book by topic experts from around the globe. It addresses next generation technologies and architectures, with the focus on networks, services, and management. Key topics include: Opportunities and challenges of next generation telecommunications networks, services, and management Tri/Quad Play and IP-based networks and services Fault, Configuration, Accounting, Performance, and Security (FCAPS) requirements Convergence and an important convergence vehicle, IP Multimedia Subsystem (IMS) Next generation operations and network management architecture Ad hoc wireless and sensor networks and their management Next generation operations and network management standards from a strategic perspective A defining look at the future in this field This book will serve as a contemporary reference for the growing global community of telecommunication and information professionals in industry, government, and academia. It will be important to faculty and graduate students of telecommunications as a graduate textbook.

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Solidification and Crystallization Processing in Metals and Alloys Hasse Fredriksson KTH, Royal Institute of Technology, Stockholm, Sweden Ulla Åkerlind University of Stockholm, Sweden Solidification or crystallization occurs when atoms are transformed from the disordered liquid state to the more ordered solid state, and is fundamental to metals processing. Conceived as a companion volume to the earlier works, Materials Processing during Casting (2006) and Physics of Functional Materials (2008), this book analyzes solidification and crystallization processes in depth. Starting from the thermodynamic point of view, it gives a complete description, taking into account kinetics and mass transfer, down to the final structure. Importantly, the book shows the relationship between the theory and the experimental results. Topics covered include: Fundamentals of thermodynamics Properties of interfaces Nucleation Crystal growth – in vapours, liquids and melts Heat transport during solidification processes Solidification structures – faceted, dendritic, eutectic and peritectic Metallic glasses and amorphous alloy melts Solidification and Crystallization Processing in Metals and Alloys features many solved examples in the text, and exercises (with answers) for students. Intended for Masters and PhD students as well as researchers in Materials Science, Engineering, Chemistry and Metallurgy, it is also a valuable resource for engineers in industry.

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Now in its 4th edition, this book remains the ultimate reference for all questions regarding solvents and solvent effects in organic chemistry. Retaining its proven concept, there is no other book which covers the subject in so much depth, the handbook is completely updated and contains 15% more content, including new chapters on «Solvents and Green chemistry», «Classification of Solvents by their Environmental Impact», and «Ionic Liquids». An essential part of every organic chemist's library.

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The book focuses on mobile agents, which are computer programs that can autonomously migrate between network sites. This text introduces the concepts and principles of mobile agents, provides an overview of mobile agent technology, and focuses on applications in networking and distributed computing.

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The combination of supramolecular chemistry, inorganic solids, and nanotechnology has already led to significant advances in many areas such as sensing, controlled motion, and delivery. By making possible an unprecedented tunability of the properties of nanomaterials, these techniques open up whole new areas of application for future supramolecular concepts. The Supramolecular Chemistry of Organic–Inorganic Hybrid Materials gathers current knowledge on the subject and provides an overview of the present state and upcoming challenges in this rapidly growing, highly cross- or interdisciplinary research field. The book details how these designed materials can improve existing materials or generate novel functional features such as chemical amplification, cooperative binding and signal enhancement that are difficult or not at all achievable by classical organic supramolecular chemistry. It also discusses issues related to nanofabrication or nanotechnology such as the directed and controlled assembly or disassembly, biomimetic functions and strategies, and the gating and switching of surface functions or morphology.

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Detailed coverage of advanced combustion topics from the author of Principles of Combustion, Second Edition Turbulence, turbulent combustion, and multiphase reacting flows have become major research topics in recent decades due to their application across diverse fields, including energy, environment, propulsion, transportation, industrial safety, and nanotechnology. Most of the knowledge accumulated from this research has never been published in book form—until now. Fundamentals of Turbulent and Multiphase Combustion presents up-to-date, integrated coverage of the fundamentals of turbulence, combustion, and multiphase phenomena along with useful experimental techniques, including non-intrusive, laser-based measurement techniques, providing a firm background in both contemporary and classical approaches. Beginning with two full chapters on laminar premixed and non-premixed flames, this book takes a multiphase approach, beginning with more common topics and moving on to higher-level applications. In addition, Fundamentals of Turbulent and Multiphase Combustion: Addresses seven basic topical areas in combustion and multiphase flows, including laminar premixed and non-premixed flames, theory of turbulence, turbulent premixed and non-premixed flames, and multiphase flows Covers spray atomization and combustion, solid-propellant combustion, homogeneous propellants, nitramines, reacting boundary-layer flows, single energetic particle combustion, and granular bed combustion Provides experimental setups and results whenever appropriate Supported with a large number of examples and problems as well as a solutions manual, Fundamentals of Turbulent and Multiphase Combustion is an important resource for professional engineers and researchers as well as graduate students in mechanical, chemical, and aerospace engineering.

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One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.

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Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

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