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Cellular domains play vital roles in a wide range of cellular functions. Defining cellular domains and understanding the molecular basis of their formation is essential to the study of cell functionality. This authoritative reference provides the most comprehensive analysis available on cellular domains, with emphasis on the definition and molecular composition of the domain as well as the functional implications of domain organization.

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Today Europe finds itself in a crisis that casts a dark shadow over an entire generation. The seriousness of the crisis stems from one core political contradiction at the heart of the European project: namely, that what urgently needs to be done is also extremely unpopular and therefore virtually impossible to do democratically. What must be done – and almost everyone agrees in principle on the measures that would be needed to deal with the financial crisis – cannot be sold to the voting public of the core member states, which so far have been less affected by the crisis than those on the periphery, nor can the conditions that core members try to impose be easily sold to voters in the deficit countries. The European Union is therefore becoming increasingly disunited, with deepening divides between the German-dominated ‘core’ and the southern ‘periphery’, between the winners and the losers of the common currency, between the advocates of greater integration and the anti-Europeans, between the technocrats and the populists. Europe finds itself trapped by the deepening divisions that are opening up across the Continent, obstructing its ability to deal with a crisis that has already caused massive social suffering in the countries of the European periphery and is threatening to derail the very project of the European Union. In this short book, Claus Offe brings into sharp focus the central political problem that lies at the heart of the EU and shackles its ability to deal with the most serious crisis of its short history.

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Why Philosophize? is a series of lectures given by Jean-François Lyotard to students at the Sorbonne embarking on their university studies. The circumstances obliged him to be both clear and concise: at the same time, his lectures offer a profound and far-reaching meditation on how essential it is to philosophize in a world where philosophy often seems irrelevant, outdated, or inconclusive. Lyotard begins by drawing on Plato, Proust and Lacan to show that philosophy is a never-ending desire – for wisdom, for the ‘other’. In the second lecture he draws on Heraclitus and Hegel to explore the close relation between philosophy and history: the same restlessness, the same longing for a precarious unity, drives both. In his third lecture, Lyotard examines how philosophy is a form of utterance, both communicative and indirect. Finally, he turns to Marx, exploring the extent to which philosophy can be a transformative action within the world. These wonderfully accessible lectures by one of the most influential philosophers of the last 50 years will attract a wide readership, since, as Lyotard says, ‘How can one not philosophize?’ They are also an excellent introduction to Lyotard’s mature thought, with its emphasis on the need for philosophy to bear witness, however obliquely, to a recalcitrant reality.

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The French philosopher Jacques Rancière is well known across the world for his groundbreaking contributions to aesthetic and political theory and for his radical rethinking of the question of equality. This much-needed new collection situates Rancière's thought in a range of practical and theoretical contexts. These specially commissioned essays cover the complete history of Rancière's work and reflect its interdisciplinary reach. They span his early historical research of the 1960s and '70s, his celebrated critique of pedagogy and his later political theory of dissensus and disagreement, as well as his ongoing analysis of literature and 'the aesthetic regime of art'. Rancière's resistance to psychoanalytic thinking is also explored, as are his most recent publications on film and film theory. Contributors include Tom Conley, Carolyn Steedman, Geneviève Fraisse, Jean-Luc Nancy, Jeremy Lane, and many more. The book also includes a brand new interview with Rancière, reflecting on his intellectual project and developing new lines of thought from his latest major work, Aisthesis. Rancière Now will be essential reading for students and scholars across the humanities and social sciences; it will stimulate and inspire discussion of Rancière’s work for years to come.

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In this new book, Mark Wheeler offers the first in-depth analysis of the history, nature and global reach of celebrity politics today. Celebrity politicians and politicized celebrities have had a profound impact upon the practice of politics and the way in which it is now communicated. New forms of political participation have emerged as a result and the political classes have increasingly absorbed the values of celebrity into their own PR strategies. Celebrity activists, endorsers, humanitarians and diplomats also play a part in reconfiguring politics for a more fragmented and image-conscious public arena. In academic circles, celebrity may be viewed as a ‘manufactured product’; one fabricated by media exposure so that celebrity activists are no more than ‘bards of the powerful.’ Mark Wheeler, however, provides a more nuanced critique contending that both celebrity politicians and politicized stars should be defined by their ‘affective capacity’ to operate within the public sphere. This timely book will be a valuable resource for students of media and communication studies and political science as well as general readers keen to understand the nature and reach of contemporary celebrity culture.

Аннотация

Proxy wars represent a perennial strand in the history of conflict. The appeal of ‘warfare on the cheap’ has proved an irresistible strategic allure for nations through the centuries. However, proxy wars remain a missing link in contemporary war and security studies. In this timely book Andrew Mumford sheds new light on the dynamics and lineage of proxy warfare from the Cold War to the War on Terror, whilst developing a cogent conceptual framework to explain their appeal. Tracing the political and strategic development of proxy wars throughout the last century, they emerge as a dominant characteristic of contemporary conflict. The book ably shows how proxy interventions often prolong existing conflicts given the perpetuity of arms, money and sometimes proxy fighters sponsored by third party donors. Furthermore, it emphasizes why, given the direction of the War on Terror, the rise of China as a global power, and the prominence now achieved by non-state actors in the ‘Arab Spring’, the phenomenon of proxy warfare is increasingly relevant to understandings of contemporary security. Proxy Warfare is an indispensable guide for students and scholars interested in the evolution and potential future direction of war and conflict in the modern world.

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The Posthuman offers both an introduction and major contribution to contemporary debates on the posthuman. Digital 'second life', genetically modified food, advanced prosthetics, robotics and reproductive technologies are familiar facets of our globally linked and technologically mediated societies. This has blurred the traditional distinction between the human and its others, exposing the non-naturalistic structure of the human. The Posthuman starts by exploring the extent to which a post-humanist move displaces the traditional humanistic unity of the subject. Rather than perceiving this situation as a loss of cognitive and moral self-mastery, Braidotti argues that the posthuman helps us make sense of our flexible and multiple identities. Braidotti then analyzes the escalating effects of post-anthropocentric thought, which encompass not only other species, but also the sustainability of our planet as a whole. Because contemporary market economies profit from the control and commodification of all that lives, they result in hybridization, erasing categorical distinctions between the human and other species, seeds, plants, animals and bacteria. These dislocations induced by globalized cultures and economies enable a critique of anthropocentrism, but how reliable are they as indicators of a sustainable future? The Posthuman concludes by considering the implications of these shifts for the institutional practice of the humanities. Braidotti outlines new forms of cosmopolitan neo-humanism that emerge from the spectrum of post-colonial and race studies, as well as gender analysis and environmentalism. The challenge of the posthuman condition consists in seizing the opportunities for new social bonding and community building, while pursuing sustainability and empowerment.

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WAS BEDEUTET DER MIND MALUS? Die unverbesserlichen Schwachen unseres Verstandes. WAS KANN MAN DAGEGEN TUN? Nichts. Im Gegenteil. Man sollte sie nutzen. NUTZEN WOFUR? Fur die Wirkung auf andere. Fur wirkungsvolles Kommunizieren. DAS IST UNGLAUBLICH. Unglaublich. Ja, vielleicht. Zumindest uberraschend. UBERRASCHEND FUR WEN? Fur alle. Besonders fur Padagogen, Politiker, Manager, Kulturschaffende. Und ganz besonders fur die Experten in Marketing, Werbung, Design und Markengestaltung. Kolonat Noss – ehemaliger Creative Director, heute Texter, Kommunikations- und Markenberater – beschreibt eine bisher unbekannte Ressource. Doch wie jede Ressource hat der Mind Malus seinen Preis. Er fordert den Abschied von eingefahrenen Denkweisen. Zentrale Themen des Buches sind Wahrnehmung, Informationsverarbeitung und -selektion, Wissen, Verstand, Leitbilder und menschliche Entscheidungen und ihre Wirkung auf Kommunikation, Wirtschaft, Kunst, Kultur und Bildung, Strategie, Marke und Markenmanagement, Unternehmensfuhrung, Unternehmenskommunikation, Personalwesen, Design, Marketing und Vertrieb.

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Dieses Buch unterscheidet sich deutlich von anderen Werken zu den Themen Ideenfindung, Problemlosen und Innovation: Die beschriebene Methodik funktioniert allein und im Team, mit erheblich geringerem Aufwand und sie wirkt fur technische und andere Systeme. Das Buch beschreibt, wie man Ziele findet und optimiert, wie man zum Losen von Problemen die richtigen Mittel und unterschiedliche Abstraktionsniveaus einsetzt, wie man Widerspruche und Fragestellungen so darstellt, dass Losungen manchmal ganz einfach erscheinen, wie man Systeme optimal strukturiert und wie man schlie?lich auch faire, uberzeugende Auswege bei unlosbaren Problemen findet. Da die – unter dem Namen PROMETIK bekannte – Methodik auf einem Systemansatz basiert, ist sie fur alle Arten von Produkten und Systemen geeignet. Zielgruppen des Buchs sind somit nicht nur Ingenieure, Techniker und Naturwissenschaftler, sondern auch Wirtschafts- und Sozialwissenschaftler sowie alle anderen Personen, die an der Entwicklung und Optimierung von Produkten, Strukturen, Systemen oder Strategien beteiligt sind.

Аннотация

Totally Integrated Automation ist das Konzept, nach dem SIMATIC Maschinen, fertigungstechnische Anlagen und verfahrenstechnische Prozesse steuert. Am Beispiel der speicherprogrammierbaren Steuerung S7-300/400 bietet dieses Buch einen umfassenden und aktuellen Einstieg in die Arbeitsweise und den Aufbau eines modernen Automatisierungssystems. Daruber hinaus gibt das Buch Einblick in Projektierung und Parametrierung der Controller und der dezentralen Peripherie, erlautert die Kommunikation uber Netzverbindungen inklusive PROFINET IO und beschreibt die Moglichkeiten fur das Bedienen und Beobachten einer Anlage. Als zentrales Automatisierungswerkzeug verwaltet STEP 7 alle anfallenden Aufgaben und stellt zusatzlich mehrere text- und grafikorientierte SPS-Programmiersprachen zur Verfugung. Welche Sprachen es gibt und was sie unterscheidet, daruber erfahrt der Leser mehr in diesem Buch. In der vierten Auflage werden neben der Aktualisierung der dezentralen Peripherie und der HMI-Gerate erstmals das neue Automatisierungssystem S7-1200 und die Engineeringsoftware STEP 7 Basic beschrieben. Das Buch ist hervorragend geeignet fur alle, die sich ohne gro?e Vorkenntnisse schnell in das Gebiet der speicherprogrammierbaren Steuerungen einarbeiten mochten.