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      3.7.4 Genetic Health Registries

Many owners and veterinarians wonder if a particular medical issue observed in a companion animal is genetically controlled and related to its breed, sex, growth rate and size, age, or diet. Health registries can help answer those questions. In their simplest form, genetic health registries are repositories of the results obtained from either phenotypic or genetic health screening tests (see 3.4 Predicting and Eliminating Disease Traits). By recording and compiling the information in an accessible formant, owners, breeders, and veterinary practitioners can use that to inform decisions. Genetic health registries provide an important resource for the veterinary community by cataloging diseases of a population of animals (Table 3.7.1), permitting the development of informed treatment plans, and illuminating trends of emerging diseases.

Table 3.7.1 The top 11 breeds with the highest prevalence of elbow dysplasia by breed for those breeds with at least 50 evaluations from 1974 thru 2018

      Source: Data from the OFA Canine Health Information Center health registry (www.ofa.org).

Breed	Rank	Number of evaluations	% Normal	% Overall dysplastic	% Grade 1 dysplasia	% Grade 2 dysplasia	% Grade 3 dysplasia
Chow chow	1	1248	50	49	25	17	6
Pug	2	216	59	41	26	13	2
Rottweiler	3	20 177	61	39	30	8	1
Bulldog	4	497	62	37	25	10	1
Fila Brasileiro	5	220	68	32	19	10	3
Boerboel	6	246	70	30	17	8	5
Black Russian terrier	7	767	72	27	19	7	1
Bernese mountain dog	8	17 869	73	27	18	7	3
Otterhound	9	137	73	27	22	4	1
Chinese shar‐pei	10	852	74	25	14	9	3
Newfoundland	11	8394	76	24	15	5	3

A primary objective of a registry is to provide a resource for breeders seeking health information on potential sires or dams. Another objective is to enable prospective owners to research the health of a breed in general or the parents and their relatives of a particular companion pet being considered. For example, Table 3.7.2 presents the health information of a dog of interest. In this example, for each dog, its registration number, birth date, and sex are listed followed by any health tests recorded. This particular dog has passed all its health clearances, as have a majority of its relatives. Health registries have the greatest value with broad participation; vast amounts of data provide the necessary power to predict outcomes and analyze trends.

Table 3.7.2 Health information on a dog of interest along with that of its sire, dam, and half siblings

      Source: Data from www.ofa.org.

Dog of interest	Registration	Birthdate	Sex	Relation	Hipsa	Elbowb	Eyesc	Thyroidd
Larentia di Villa Roma	DN09589103	Dec 16 2004	F	Self	BT‐4753G27	BT‐EL2046F27	BT‐EYE316	BT‐TH315/27
Sire/Dam
Neartic de la Grande Lande	DL75874001	Mar 13 1997	M	Sire	BT‐3264G32	BT‐EL754M32	BT‐2233 Скачать книгу В начало < 99 100 101 102 103 104 105 106 107 108 > В конец