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Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes. The discipline is closely related and linked mainly to the broader field of pharmacoepidemiology, but also to health outcomes research, pharmacovigilance and health economics. Drug Utilization Research is a unique, practical guide to the assessment and evaluation of prescribing practices and to interventions to improve the use of medicines in populations. Edited by an international expert team from the International Society for Pharmacoepidemiology (ISPE), DUR is the only title to cover both the methodology and applications of drug utilization research and covers areas such as health policy, specific populations, therapeutics and adherence.

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The elderly represent the fastest growing segment of the population in developed countries, reflected in the patient population presenting to EDs and hospitals. These patients more often than not have greater co-morbidities, more complicated workups and utilize more laboratory and radiologic services. This text is designed to teach emergency physicians how best to care for this specific demographic of patients. It addresses physiologic changes, high-risk conditions, and atypical presentations associated with elderly patients in the ED that result in frequent misdiagnosis or delays in diagnosis. It instructs the readers how best to care for elderly patients in order to minimize morbidity and mortality, addressing some of the difficult psychosocial issues that confront health care providers that care for elderly patients, such as psychiatric disease and end-of-life care. The utility of this text is not limited to emergency physicians, but it should be useful to all health care providers involved in the treatment of elderly patients with acute medical or surgical conditions.

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Female genital plastic surgery has become an increasingly sought-after option for women seeking ?improvement? in genital appearance, relief from discomfort, and increased sexual pleasure. These surgeries are a combination of gynecologic, plastic, and cosmetic procedures. Every year sees a higher demand for physicians properly trained and able to perform them. This unique text from the acknowledged experts in the field covers; the anatomy of the area the specific surgical procedures and all their variations patients? rationales for surgery training guidelines and ethical issues outcome statistics sexual issues patient selection potential risks and complications. Examining the issues from individual patient?s perspectives, it is written in an academic but easy-to-read style with understandable and unambiguous drawings and photographs. It contains a step-by-step surgical approach, how to best select the right surgical candidates, how to treat this select group of patients, the sexual issues involved, how to individualize techniques for each specific patient, how to deal with criticism from colleagues or journalists, psychosexual issues, and patient protection.

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EPD Congress is an annual collection of conference proceedings that addresses extraction and processing metallurgy. The papers in this book are drawn from symposia held at the 2015 Annual Meeting of The Minerals, Metals & Materials Society. The 2015 edition includes papers from the following symposia: Materials Processing Fundamentals Solar Cell Silicon High-Temperature Electrochemistry II

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Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

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Written by a team of international experts, Extremes and Recurrence in Dynamical Systems presents a unique point of view on the mathematical theory of extremes and on its applications in the natural and social sciences. Featuring an interdisciplinary approach to new concepts in pure and applied mathematical research, the book skillfully combines the areas of statistical mechanics, probability theory, measure theory, dynamical systems, statistical inference, geophysics, and software application. Emphasizing the statistical mechanical point of view, the book introduces robust theoretical embedding for the application of extreme value theory in dynamical systems. Extremes and Recurrence in Dynamical Systems also features: • A careful examination of how a dynamical system can serve as a generator of stochastic processes • Discussions on the applications of statistical inference in the theoretical and heuristic use of extremes • Several examples of analysis of extremes in a physical and geophysical context • A final summary of the main results presented along with a guide to future research projects • An appendix with software in Matlab® programming language to help readers to develop further understanding of the presented concepts Extremes and Recurrence in Dynamical Systems is ideal for academics and practitioners in pure and applied mathematics, probability theory, statistics, chaos, theoretical and applied dynamical systems, statistical mechanics, geophysical fluid dynamics, geosciences and complexity science. VALERIO LUCARINI, PhD, is Professor of Theoretical Meteorology at the University of Hamburg, Germany and Professor of Statistical Mechanics at the University of Reading, UK. DAVIDE FARANDA, PhD, is Researcher at the Laboratoire des science du climat et de l’environnement, IPSL, CEA Saclay, Université Paris-Saclay, Gif-sur-Yvette, France. ANA CRISTINA GOMES MONTEIRO MOREIRA DE FREITAS, PhD, is Assistant Professor in the Faculty of Economics at the University of Porto, Portugal. JORGE MIGUEL MILHAZES DE FREITAS, PhD, is Assistant Professor in the Department of Mathematics of the Faculty of Sciences at the University of Porto, Portugal. MARK HOLLAND, PhD, is Senior Lecturer in Applied Mathematics in the College of Engineering, Mathematics and Physical Sciences at the University of Exeter, UK. TOBIAS KUNA, PhD, is Associate Professor in the Department of Mathematics and Statistics at the University of Reading, UK. MATTHEW NICOL, PhD, is Professor of Mathematics at the University of Houston, USA. MIKE TODD, PhD, is Lecturer in the School of Mathematics and Statistics at the University of St. Andrews, Scotland. SANDRO VAIENTI, PhD, is Professor of Mathematics at the University of Toulon and Researcher at the Centre de Physique Théorique, France.

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Invasive species have a critical and growing effect upon natural areas. They can modify, degrade, or destroy wildland ecosystem structure and function, and reduce native biodiversity. Landscape-level solutions are needed to address these problems. Conservation biologists seek to limit such damage and restore ecosystems using a variety of approaches. One such approach is biological control: the deliberate importation and establishment of specialized natural enemies, which can address invasive species problems and which should be considered as a possible component of restoration. Biological control can be an effective tool against many invasive insects and plants but it has rarely been successfully employed against other groups. Safety is of paramount concern and requires that the natural enemies used be specialized and that targeted pests be drivers of ecological degradation. While modern approaches allow species to be selected with a high level of security, some risks do remain. However, as in all species introductions, these should be viewed in the context of the risk of failing to reduce the impact of the invasive species. This unique book identifies the balance among these factors to show how biological control can be integrated into ecosystem restoration as practiced by conservation biologists. Jointly developed by conservation biologists and biological control scientists, it contains chapters on matching tools to management goals; tools in action; measuring and evaluating ecological outcomes of biological control introductions; managing conflict over biological control; and includes case studies as well as an ethical framework for integrating biological control and conservation practice. Integrating Biological Control into Conservation Practice is suitable for graduate courses in invasive species management and biological control, as well as for research scientists in government and non-profit conservation organizations.

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A fully comprehensive examination of state-of-the-art technologies for measurement at the small scale • Highlights the advanced research work from industry and academia in micro-nano devices test technology • Written at both introductory and advanced levels, provides the fundamentals and theories • Focuses on the measurement techniques for characterizing MEMS/NEMS devices

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This book provides an overview of the newly emerged and highly interdisciplinary field of printed electronics • Provides an overview of the latest developments and research results in the field of printed electronics • Topics addressed include: organic printable electronic materials, inorganic printable electronic materials, printing processes and equipments for electronic manufacturing, printable transistors, printable photovoltaic devices, printable lighting and display, encapsulation and packaging of printed electronic devices, and applications of printed electronics • Discusses the principles of the above topics, with support of examples and graphic illustrations • Serves both as an advanced introductory to the topic and as an aid for professional development into the new field • Includes end of chapter references and links to further reading