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Agree

      3 Neutral

      2 Disagree

      1 Strongly Disagree

      1. Is the High-throughput virtual screening scope manageable?

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      2. Are required metrics defined, what are they?

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      3. The political context: who holds power?

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      4. How do you manage changes in High-throughput virtual screening requirements?

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      5. Is the team adequately staffed with the desired cross-functionality? If not, what additional resources are available to the team?

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      6. What was the context?

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      7. Has a high-level ‘as is’ process map been completed, verified and validated?

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      8. How did the High-throughput virtual screening manager receive input to the development of a High-throughput virtual screening improvement plan and the estimated completion dates/times of each activity?

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      9. What is the worst case scenario?

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      10. Is the current ‘as is’ process being followed? If not, what are the discrepancies?

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      11. Will team members regularly document their High-throughput virtual screening work?

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      12. How will the High-throughput virtual screening team and the group measure complete success of High-throughput virtual screening?

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      13. How will variation in the actual durations of each activity be dealt with to ensure that the expected High-throughput virtual screening results are met?

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      14. What High-throughput virtual screening services do you require?

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      15. What is the scope of High-throughput virtual screening?

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      16. Have all of the relationships been defined properly?

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      17. How do you catch High-throughput virtual screening definition inconsistencies?

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      18. How do you keep key subject matter experts in the loop?

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      19. In what way can you redefine the criteria of choice clients have in your category in your favor?

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      20. Has a team charter been developed and communicated?

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      21. Has a project plan, Gantt chart, or similar been developed/completed?

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      22. How do you build the right business case?

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      23. Is special High-throughput virtual screening user knowledge required?

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      24. Is High-throughput virtual screening required?

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      25. How does the High-throughput virtual screening manager ensure against scope creep?

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      26. Is there regularly 100% attendance at the team meetings? If not, have appointed substitutes attended to preserve cross-functionality and full representation?

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      27. Has your scope been defined?

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      28. Have all basic functions of High-throughput virtual screening been defined?

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      29. Who are the High-throughput virtual screening improvement team members, including Management Leads and Coaches?

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      30. Is there a clear High-throughput virtual screening case definition?

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      31. What is in scope?

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      32. Are approval levels defined for contracts and supplements to contracts?

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      33. What is in the scope and what is not in scope?

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      34. What specifically is the problem? Where does it occur? When does it occur? What is its extent?

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      35. Is there a High-throughput virtual screening management charter, including stakeholder case, problem and goal statements, scope, milestones, roles and responsibilities, communication plan?

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      36. Is the team formed and are team leaders (Coaches and Management Leads) assigned?

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      37. What are the requirements for audit information?

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      38. Are the High-throughput virtual screening requirements testable?

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      39. Who is gathering information?

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      40. What scope do you want your strategy to cover?

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      41. What knowledge or experience is required?

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      42. Is it clearly defined in and to your organization what you do?

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      43. Will a High-throughput virtual screening production readiness review be required?

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      44. How have you defined all High-throughput virtual screening requirements first?

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      45. Has everyone on the team, including the team leaders, been properly trained?

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      46. Does the team have regular meetings?

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      47. How do you hand over High-throughput virtual screening context?

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      48. What are the compelling stakeholder reasons for embarking on High-throughput virtual screening?

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      49. How do you gather requirements?

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      50. What is the scope of the High-throughput virtual screening effort?

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      51. When is/was the High-throughput virtual screening start date?

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      52. When are meeting minutes sent out? Who is on the distribution list?

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      53. Has/have the customer(s) been identified?

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