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Are you a student or resident taking a gastroenterology rotation, a fellow in gastroenterology training, or a practitioner approaching GI recertification? Do you need a rapid-reference, essential guide to help refresh your clinical knowledge? Essentials of Gastroenterology provides students, residents, and gastroenterologists, especially those in training, with a highly practical, concise guide to the GI system and its major diseases. Full color throughout, the book covers all conditions encountered during GI training and education programs and in the clinical setting. With a strong focus on the clinical aspects of GI disease, it highlights the specific scenarios you will be presented with when managing your patients on the wards. Each section looks at a particular area of the GI tract, with each disease-related chapter examining the following: overview of normal function physiology and pathophysiology clinical presentation differential diagnosis diagnostic tests treatment/management options In addition, there is a section dedicated to the most common symptoms that patients present with, as well as a picture gallery of common GI conditions such as peptic ulcers and inflammatory bowel disease. Drs. Sitaraman and Friedman have ensured that the key emphasis throughout is on providing easy-to-assimilate, rapid-reference information on each GI condition, achieved through the use of color-coded text features such as key facts, potential pitfalls, and practice tips. Packed with multiple choice questions and specific clinical case studies, the book also draws upon the guidelines and recommendations of the world’s leading gastroenterology societies – the AGA, ASGE, ACG, BSG, WGO, and UEGF.

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The fifth edition of this highly successful book provides students with an essential introduction to the molecular genetics of bacteria covering the basic concepts and the latest developments. It is comprehensive, easy to use and well structured with clear two-colour diagrams throughout. Specific changes to the new edition include: More detail on sigma factors, anti-sigma factors and anti-anti sigma factors, and the difference in the frequency of sigma factors in bacteria Expand material on integrons as these are becoming increasingly important in antibiotic resistance Enhanced treatment of molecular phylogeny Complete revision and updating of the final chapter on ‘Gene Mapping and Genomics’ Two-colour illustrations throughout. The focus of the book remains firmly on bacteria and will be invaluable to students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.

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Clinical Dilemmas in Diabetes provides evidence-based clinical guidance on the most common and problematic areas of concern encountered in diagnosing, treating and managing patients with diabetes. Each chapter is highly topical and has been selected due to current interest, specific recent developments, and areas of controversy. This valuable guide provides assistance in managing the life-long treatment of diabetes and the complications that often develop in patients. Clinical Dilemmas in Diabetes guides the medical team in their decision-making, particularly when there are conflicts in the treatment for the disease and the complications. Part of the Clinical Dilemmas series, the well-focused chapter structure allows for quick retrieval of information, and each opens with a “Learning Points” box to aid easy assimilation of the main issues. With a leading team of contributors and editors, Professor Robert A. Rizza is the immediate Past-President of the American Diabetes Association. This book is perfect for use on the wards and clinics as well as for self-study by diabetologists, diabetes specialist nurses, endocrinologists, GPs and cardiologists.

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Preterm birth is a major challenge in perinatal health care. Most perinatal deaths occur in preterm infants, and preterm birth is an important risk factor for neurological damage, including cerebral palsy. This ABC covers all the latest information on this complex and multidisciplinary area from obstetric issues to immediate care of preterm infants, respiratory complications, and how to provide support to the parents and relatives of the preterm infant. With its clear explanation and many illustrations, general practitioners, medical students, paediatricians starting their postgraduate training, nurses, and midwives will find ABC of Preterm Birth an excellent reference.

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Prehospital care is a growing area in medicine, and emergency treatments are becoming more sophisticated as the potential to save lives grow. The fourth edition of this ABC has been thoroughly updated and includes new chapters on nuclear and biological emergencies. Each chapter gives concise and clear guidance and is accompanied by excellent photographs and diagrams. Edited and written by leading UK trauma authorities, this is a truly comprehensive and practical book for everyday use by emergency medicine staff, nurses, hospital doctors, paramedics, and ambulance services. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

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Successful management of eye disease relies on the veterinarian’s ability to identify ocular features and distinguish pathologic changes. Atlas of Feline Ophthalmology, Second Edition is an invaluable diagnostic reference, providing high-quality color photographs for comparison with a presenting complaint. Presenting 394 photographs illustrating both normal and pathologic ocular conditions, this Second Edition offers a current, complete reference on ocular diseases, adding conditions recognized since publication of the first edition, a broader geographic scope, and many new images with improved quality. Carefully designed for easy reference, the contents are divided into sections corresponding to specific anatomical structures of the eye. A useful appendix new to this edition groups figures by etiology, making it easy to find every image associated with a specific agent or disease. Atlas of Feline Ophthalmology, Second Edition is a useful tool aiding general practitioners in diagnosing eye disease in cats.

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The American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an «unparalleled collection of knowledge.» Since the first edition's publication, advances have been made in diagnosis, understanding, and treatment of genetic syndromes, resulting in the potential for a higher quality of life for individuals affected. Management of Genetic Syndromes, Second Edition incorporates all the most recent developments in knowledge about and management of the most common genetic syndromes seen in children and adults. Expanded to cover twenty-five new syndromes, this comprehensive new edition also features thorough updates of chapters from the first edition. Edited by two of the field's most highly esteemed experts, each chapter is written by an expert with extensive direct professional experience with that disorder and includes detailed coverage of: Incidence Etiology and pathogenesis Natural history Diagnostic criteria and diagnostic testing, including photographs of distinctive physical findings Differential diagnosis Evaluation Management throughout life References and resources, including family support organizations Written to be clear and accessible to medical generalists and specialists, as well as allied health and education professionals and families, Management of Genetic Syndromes, Second Edition provides a unique and up-to-date resource for this rapidly developing field.

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This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

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Of all the complications which arise from diabetes, cardiovascular complications are by far the most prevalent and the most deadly. Authored by some of the world's leading names in this area, this outstanding book provides all those managing diabetic patients with clinical, practical and succinct guidance to the diagnosis and management of cardiovascular complications in diabetes. With a joint endocrinology and cardiology focus, and with the very latest in clinical guidelines from the ADA, EASD, AHA, ASC and ESC, selected highlights include: – The role of new biomarkers of cardiovascular disease in diabetes – The latest on diagnosis of cardiovascular problems via vascular imaging – Hypertension and cardiovascular disease in the diabetic patient – Dyslipidaemia and its management in type 2 diabetes – Management of thrombosis, acute coronary syndrome and peripheral arterial disease in diabetes Key points, case studies and self-assessment questions allow for rapid-reference, quick understanding of all topics, thus ensuring that this is perfect reading for endocrinologists, diabetes specialists and cardiologists of all levels managing patients with diabetes and associated cardiovascular problems.

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Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.

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