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A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and «designer» drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

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How to Succeed at the Medical Interview provides candidates with a competitive edge. It reduces the likelihood of unexpected questions or situations and helps improve confidence before and during the medical interview. This new second edition includes updated content on changes to the structure of healthcare and how this affects both the application and interview process. It details the types of questions that will be asked at medical interviews and also provides improved guidance for overseas doctors and healthcare professionals and for those seeking to practice abroad. How to Succeed at the Medical Interview is the ideal guide for Foundation Programme trainees, Specialist Registrars and General Practitioner trainees. It is also valuable for healthcare professionals facing competitive medical interviews at any stage of their career.

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Multicultural Handbook of Food, Nutrition and Dietetics is the must have practical resource for dietitians, nutritionists and students working with both well settled but also recently migrated ethnic groups. Written by a team of authors drawn from the British Dietetic Association's Specialist Multicultural Nutrition Group the book provides in-depth information to equip the reader in the provision of nutrition advice to minority groups. Spanning a broad range of cultural groups the book seeks to consider religious and cultural requirements in relation to traditional diets; research on migration studies and chronic disease states; and nutrition and dietetic treatment in relation to key chronic diseases.

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Effective stroke therapy can be improved through real-time monitoring of the neurological and cardiovascular responses to treatment. This requires crucial knowledge on behalf of both the sonographer and stroke physician to make the best decisions for the patient so as to minimize the damage caused by the original stroke and the risk of further stroke. Cerebrovascular Ultrasound in Stroke Prevention and Treatment, Second Edition, takes a practical approach to the examination of patients, the interpretation of ultrasound studies and the application of cerebrovascular ultrasound in the development of management and treatment studies, assisting neurologists, radiologists, and ultrasonographers in stroke therapy.

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Effective pain management requires increasingly specialized knowledge. Multidisciplinary information is required if you intend to practice pain management at a high level of effectiveness. This includes anatomy and physiology, pain syndromes, diagnosis and management, and the correct use of interventional techniques. Pain-Relieving Procedures: The Illustrated Guide provides you with a step-by-step guide to interventional techniques underpinned by a solid multidisciplinary knowledge base. The text is enhanced by the wide use of illustrations, including amazing color 3D-CT images that enable you to easily visualize anatomy. The first part of the book gives the fundamentals you need for modern pain practice. The second part describes all commonly used procedures, using a head-to-toe organization. The head The neck The thoracic region The thoraco-abdominal region The lumbar region The pelvic and sacral region A special chapter covers more advanced techniques such as continuous analgesia, spinal cord and sacral stimulation, vertebroplasty and kyphoplasty. Each procedure is described using a template that includes anatomy, indications, contraindications, technique and complications. Helpful hints throughout will help you refine your practice to achieve better results. Concise, straightforward, and indispensable, Pain-Relieving Procedures: The Illustrated Guide provides the most effective interventional methods for those practicing pain management.

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The field of oncology benefits from several large-scale reference books and a host of monographs dedicated to specific cancers. However, truly excellent practice and review books are, surprisingly, quite scarce. Outside of a scant handful of books and online reference tools that offer clinical response practice and board review in a basic question and answer format, there are no resources that offer a robust, engaging, fully referenced tool for these vital activities in every oncologist’s and oncology trainee’s work. This print and electronic book seeks to fill that void, offering comprehensive question-and-answer style content that covers the entire specialty of oncology and provides practicing oncologists with a fascinating and immediately applicable compendium of vital information dealing with a well-balanced selection of common and uncommon cancers. At the heart of this book is the editor’s and authors’ desire to overcome the controversies and barriers to practice that usually emerge following the appearance of new data. In every section, the user is guided toward collaboration in ongoing clinical research – for example, via discussions of well-designed ongoing clinical trials in each specific area. Developed with both the teacher and learner in mind, this book also offers trainees and fellows an excellent opportunity to enhance their preparation for the ABIM oncology fellowship exam as well as for the oncology boards. It will also be an extremely useful tool for oncologists working toward the recertification exam. This comprehensive, beefy book includes hundreds of painstakingly developed multiple-choice and mini-case-based questions covering the principles of medical oncology, malignant hematology, surgical oncology, and radiation oncology. It also contains mini-cases and questions dealing with the biology, diagnosis, classification, staging, and multidisciplinary treatment of cancers at every anatomic site. The very latest topics are included, such as molecular techniques, targeted therapies, and translational cancer research. Concise but detailed answers are referenced to key journals and books, and evidence-based wherever possible. NCCN guidelines are also referenced as appropriate. With its powerful focus on take-home messages from and for actual clinical work, this book will help keep oncologists up to date, bridging the gaps between journal and reference literature, conferences, and their existing knowledge base.

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A vast choice of techniques and technology confronts today’s interventional cardiologists, and those who are new to angioplasty need clear and practical guidance in order to develop good habits, avoid common pitfalls and become efficient and confident practitioners. Written to provide readers with a solid grounding in the basics of percutaneous techniques by providing selective, practical knowledge and a full range of useful tools and tips, Essential Angioplasty is: Ideal for those seeking a solid foundation in percutaneous interventions Designed for ease of use and retention of information; copiously illustrated with clear «take home messages» concluding each chapter Packed with over 300 tips and tricks which readers can apply in their training and practice Based on the authors' hands-on experience in the world's leading interventional cardiology training centers and years of proven teaching experience Throughout, the authors follow the motto «keep it simple» and focus only on the information that will help the reader learn and master the relevant technique. This makes Essential Angioplasty the perfect companion for trainees and others seeking a reliable guide to achieving success in the cardiac catheterization laboratory.

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Biological psychiatry has dominated psychiatric thinking for the past 40 years, but the knowledge base of the discipline has increased substantially more recently, particularly with advances in genetics and neuroimaging. The third edition of Biological Psychiatry has been thoroughly updated taking into account these developments. As in the earlier editions of the book, there are comprehensive reviews and explanations of the latest advances in neurochemistry, neuroanatomy, genetics and brain imaging— descriptions not only of methodologies but also of the application of these in clinical settings. It is within this context that there is a considerable emphasis in the book on brain–behaviour relationships both within and without the clinical setting. This edition has been enhanced by the inclusion of new chapters, one on anxiety and another on motivation and the addictions. The chapter that relates to treatments has been extended to include the latest information on brain stimulation techniques. The overall book is well illustrated in order to help with an understanding of the text. For the third edition, Professor Michael Trimble has been joined by Professor Mark George as co-author. These are two of the world's leading biological psychiatrists who both have considerable clinical as well as research experience which they have brought to the book. Unlike multiauthored texts, it has a continuity running through it which aids understanding and prevents repetition. This book is strongly recommended for all practising psychiatrists and trainees wishing for an up-to-date, authoritative, easy to digest and acessible review of the latest advances and conceptualizations in the field. It will also appeal to neurologists interested in neuropsychiatry and biological psychiatry or the psychiatric aspects of neurological disorders, as well as other practising clinicians (psychologists, social workers, nurses) in the mental health field.

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With over 250 full colour illustrations the new 5th edition of the bestselling ABC of Dermatology covers the diagnosis and treatment of skin conditions for the non-dermatologist. It sets out the main types of clinical change that occur in and on the skin, and relates this to specific skin conditions and underlying pathological changes. It then summarises the relevant pathological processes, diagnostic features and learning points. The types of treatment are clearly differentiated – between those suitable for the patient to obtain ‘off the shelf’, on prescription, and in specialist units. The ABC of Dermatology provides the core knowledge of diagnosis and therapy of common conditions and the general principles of skin condition management. Including new chapters on drug rashes, connective tissue disease, skin tumours, practical procedures, laser treatments and a practical guide to dressings and bandages, this highly illustrated ABC is the perfect learning partner for GPs, GP registrars, junior doctors, medical students and primary care nurses.

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Chronic pain is a very common problem, impacting on many patients. Assessment and management can be challenging. The ABC of Pain focuses on the pain management issues often encountered in primary care. Covering major chronic pain presentations, such as musculoskeletal pain, low back pain and neuropathic pain, the ABC of Pain also provides guidance on the management of pain in pregnancy, children, older adults, drug dependency and the terminally ill. Beginning with an overview of the epidemiology of chronic pain, pain mechanisms and the assessment of pain, it then provides practical guidance on interventional procedures and methods of effective pain management. The ABC of Pain is a comprehensive, evidence-based reference. It is ideal for GPs, junior doctors, nurse specialists in primary care, palliative care specialists, and also hospital and hospice staff managing chronically and terminally ill patients.

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