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The synthesis of macrocycles is an art in itself. Template-controlled synthesis provides elegant access to fascinating macrocyclic structures. Polyazamacrocycles, crown ethers, cryptands, rotaxanes, knots – the range of macrocyclic compounds is as broad as their potential application as molecular switches, in ion exchange, electron transfer or catalysis. This book provides authoritative information on all aspects of template-controlled macrocyclizations. It covers in depth the current state of research on template processes – novel synthetic techniques and mechanistic approaches. The critical discussion of the diverse synthetic routes includes the detailed characterization of the broad variety of macrocyclic products. References to applications of macrocyclic compounds and over 1,500 citations make this handbook an indispensable tool for chemists in academia and industry. Researchers in organic and supramolecular chemistry, biotechnology, and inorganic chemistry will find inspiration for the design, synthesis, and myriad uses of new synthetic macrocycles.

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Saul Kripke has been a major influence on analytic philosophy and allied fields for a half-century and more. His early masterpiece, Naming and Necessity, reversed the pattern of two centuries of philosophizing about the necessary and the contingent. Although much of his work remains unpublished, several major essays have now appeared in print, most recently in his long-awaited collection Philosophical Troubles. In this book Kripke’s long-time colleague, the logician and philosopher John P. Burgess, offers a thorough and self-contained guide to all of Kripke’s published books and his most important philosophical papers, old and new. It also provides an authoritative but non-technical account of Kripke’s influential contributions to the study of modal logic and logical paradoxes. Although Kripke has been anything but a system-builder, Burgess expertly uncovers the connections between different parts of his oeuvre. Kripke is shown grappling, often in opposition to existing traditions, with mysteries surrounding the nature of necessity, rule-following, and the conscious mind, as well as with intricate and intriguing puzzles about identity, belief and self-reference. Clearly contextualizing the full range of Kripke’s work, Burgess outlines, summarizes and surveys the issues raised by each of the philosopher’s major publications. Kripke will be essential reading for anyone interested in the work of one of analytic philosophy’s greatest living thinkers.

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