The Art of Dental Suturing - A. Burak Çankaya

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tissues heal through regeneration or repair depends on the availability of the required cells, the existence of signals to be transmitted to stimulate these cells, and the distance between the wound edges. The duration of healing varies depending on local and systemic factors.

      Wound healing is managed by inflammation resulting from the complex interaction between cells, soluble substances, molecules, and perfusion. The outcome and duration of healing is estimated by the timing of these interactions and associations as well as the magnitude, severity or duration of their mutual activities. Over the past decade, significant progress has been made in exploring some of these processes. Important insights have been provided by various models used to inhibit healing processes that yield poor outcomes (i.e. non-healing wounds, chronic wounds or wounds leaving scars) and in identifying underlying mechanisms that ensure wound healing. Regeneration is preferred to reparative tissue when it comes to healing, as the former is associated with no scars and with improved function. Recent research studies have therefore focused on regenerative healing.

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