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of accident, the same attention is to be observed in the disease by inoculation as in the natural way, and the medicines recommended are the same I would use; but by inoculation there seldom is a call for any, so favourably does the distemper proceed through its several stages.

      "The crisis being over, it will be proper to purge the cattle, to air them by degrees, and to have the same regard in the management of them as is laid down in the chapter on the method of cure."

      Such are the recommendations which Layard has prescribed for those who have to practise inoculation as a preventive treatment; it would be difficult to offer an example of greater prudence or precision.

      A certain number of oxen were, by means of this inoculation, protected against the attack of the cattle disease; and this mode of treatment was, as we shall afterwards explain, adopted in Russia. Unfortunately, this rational and preventive treatment was discovered only at the end of the epizootia, when already upwards of six millions of horned cattle had fallen a sacrifice to the contagious fever.

      Curative Means.– When the first course of the disease had left no doubt of the attack, the sick animal was subjected to an appropriate diet, and restricted to liquids either as medicinal decoctions, or as alimentary beverages. The decoctions consisted of whey mixed with a little vinegar, and nitred hay. The broths, or alimentary beverages, consisted of a decoction of bread, and of water mixed with bran and meal, whether of barley, oats, or wheat.

      At this stage of the curative process, the majority of physicians recommended one or two bleedings, in order to abate the violence of the fever, and of the congestions near the nervous centres and the lungs; and as constipation prevailed at the time, they strove with the same object to empty the digestive passages, the intestines, and the stomachs, notwithstanding the difficulty that exists to produce this result in ruminating animals.

      The purgatives employed consisted of a decoction of senna, mixed with prune juice, with a little rhubarb or fresh linseed oil, infused in their drink, or applied as a clyster in warm water slightly salted. Those who practised polypharmacy administered at night a mixture of nitre, camphor, red-lead, and rhubarb, in half a pailful of warm water; and greatly did they boast of the active influence of this beverage.

      Some practitioners even endeavoured, in the first stage of the malady, to accelerate its action on the skin by giving for that purpose warm drinks, and by covering the cattle with woollen cloths, to promote perspiration; but it was generally admitted that the sick animals preferred cold drinks, and that they were particularly fond of acidulated whey.

      In the second period of the distemper, the same drinks were continued, adding thereto some theriac or Jesuit's bark, in order to lessen the frequency of the diarrhœtic evacuations. They also provoked the depurating secretions from the mouth, nose, and eyes, by repeated washings; and as those animals, in which the running was most easy and copious, seemed to be less seriously affected with the disease, they strove to increase that which flowed from the glands of the mouth by fixing a gag in the jaws, and keeping it there for several hours. This measure seemed so efficacious that a decree from the Parlement de Rouen, issued on the 13th of March, 1745, ordered the application of a gag, or bit, for three hours every day, to the cattle under treatment.

      In the third period, they sought to overcome the wasting of strength in the system by means of tonic and nutritious drinks, decoctions of centaury, Jesuit's bark, juniper berries, &c. They likewise administered emollient clysters if the evacuations were bloody.

      Moreover, they placed two or three setons, principally in the dewlap, in order to obey the signs and indications of nature —quo natura vergit, eo ducendum; as a salutary and critical eruption of the skin was at that period forcing its way. These setons were kept open with a mixture of turpentine and yolks of egg, for the purpose of encouraging the secretion. The purulent or emphysematous tumours were cut.

      But whatever means might be employed, almost all the cattle perished, and the few and rare recoveries only afforded the pessimists the satisfaction of claiming the merit of them for themselves. It was remarked, besides, that the fattest beasts were the least able to resist the effects of the distemper.

      It is hardly necessary to say, that during the whole course of the treatment, great care was taken to keep both the stables and the cattle in a perfect state of cleanliness.

      The convalescence of those animals which were cured was invariably long, and required great attention as to their food and hygienic treatment. Solid substances, roots, and forage were withheld until rumination revived; and it was only after several days of encouraging trials that the recovered animal was suffered at last to feed all day in the field, according to his pleasure.

      Such, then, was that formidable epizootia which, in the middle of the eighteenth century, swept away upwards of six millions of horned cattle, and which occasioned a loss to Europe exceeding fifty millions sterling – perhaps we might say a hundred millions – for other domestic animals, sheep, horses, &c. (as generally happens in cases of epizootia), had likewise suffered, in different degrees, from the various complaints arising from inclement seasons.

      It was certainly necessary to our purpose that we should have taken this retrospective view of the cattle disease, and it will afford us a valuable guide for the future. We may now content ourselves with bringing together the different annals in the chain of time which elapsed between Layard's treatise, which was published in 1757, and the present day. This chain of time amounts to 108 years.

V

      The typhus of Horned Cattle, which had shown itself in a manner permanent, sometimes raging at one part of the globe, sometimes at another, could not, under the unaltered conditions by which it had been generated, suspend its ravages; and though, thanks to her isolated position, England may be less exposed to it than other countries, it is, however, necessary to take note of what may serve for our instruction in the several epizootics which will pass under our view.

      Medical writers relate that contagious typhus broke out several times in Holland during the years 1768, 1769, and 1770; it also appeared in French Flanders in 1771, in Hainault in 1773. In France one particular spot was, at this period, completely rendered intact by drawing a sanitary fence about its limits, and bestowing on the cattle particular hygienic attention as a safeguard. The stables of these animals were washed, cleansed, and fumigated; spring water was given them to drink, their food was chosen with care, and a certain quantity of salt was mixed with it.

      In 1774, Holland, a cold and damp country, was once more invaded by the scourge; and the Government offered in vain a reward of 80,000 florins to any one who should discover the preventive or specific remedy for the disease.

      The typhus which, at that epoch, had likewise broken out again in the south of France, threatened to become an abiding peril to the wealth of nations. Two French authors, Vicq d'Azyr and Paulet, betook themselves earnestly to the task of collecting every document which up to that time had been published on the successive visitations of the malady, and of offering the means of preventing it. Their intention was unquestionably laudable, but the time for obtaining such a result had not yet arrived; besides which, these two writers, whatever may have been their desert, were not equal to an achievement of this character. They belonged, indeed, to that order of men who look upon the cultivation of science solely as a step to personal distinction.

      Vicq d'Azyr himself was but twenty-five years old when he issued, in 1775, his work, entitled, "Exposé des Moyens curatifs et preservatifs qui peuvent être employés contre les Maladies des Bêtes à Cornes." We should deceive ourselves if we expected to find in this exposition anything but an interesting compilation of the works already published.

      Paulet's treatise appeared likewise in 1775, under the title, "Recherches historiques et physiques sur les Maladies epizootiques, avec les Moyens d'y rémédier dans tous les Cas, publiées par ordre du Roi." Paris. Two volumes.

      After reading and reflecting on this title, as servile as it is arrogant, I might have dispensed with all examination of the work. A scientific man, whilst in the pursuit of truth, takes orders from nobody, not even from kings. Paulet, therefore, writing by order, could only produce a work of mediocrity, and such is incontestably the degree of value of his two volumes, forming, as they do, a fastidious dissertation of epizootics in general, and of those relating to cattle in particular.

      The

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