LITMIR.BIZ

Environmental Sedimentology provides a comprehensive introduction to this rapidly expanding field which addresses the functioning and dynamics of contemporary sediment systems and how these systems respond to a range of both natural and anthropogenically-induced disturbance events. considers a range of sedimentary environments; mountain and upland, fluvial, lacustrine, arid, urban, deltaic and estuarine, temperate coastal, tropical coastal, and continental shelf aspects of sediment management and remediation are also considered as are the potential impacts of on-going and future climatic and environmental change Readership: advanced level undergraduates in earth science, environmental science and physical geography, and graduate students in the earth and environmental sciences with an interest in contemporary sediment systems

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Diagenesis affects all sediments after their deposition and includes a fundamental suite of physical, chemical and biological processes that control the texture, mineralogy and fluid-flow properties of sedimentary rocks. Understanding the processes and products of diagenesis is thus a critical component in the analysis of the evolution of sedimentary basins, and has practical implications for subsurface porosity destruction, preservation and generation. This in turn is of great relevance to the petroleum and water industries, as well as to the location and nature of some economic mineral deposits. Combines key papers in sandstone diagenesis published in Sedimentology over the last 30 years. Records the development of diagenesis from the description of grain shapes through provenance, petrography and analytical geochemistry to predictive models of diagenetic process. Provides definitions and explanations of the terms and concepts used in diagenesis. If you are a member of the International Association of Sedimentologists, for purchasing details, please see: http://www.iasnet.org/publications/details.asp?code=RP4

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This handy reference introduces the subject of forecast verification and provides a review of the basic concepts, discussing different types of data that may be forecast. Each chapter covers a different type of predicted quantity (predictand), then looks at some of the relationships between economic value and skill scores, before moving on to review the key concepts and summarise aspects of forecast verification that receive the most attention in other disciplines. The book concludes with a discussion on the most important topics in the field that are the subject of current research or that would benefit from future research. An easy to read guide of current techniques with real life case studies An up-to-date and practical introduction to the different techniques and an examination of their strengths and weaknesses Practical advice given by some of the world?s leading forecasting experts Case studies and illustrations of actual verification and its interpretation Comprehensive glossary and consistent statistical and mathematical definition of commonly used terms

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The application of biologically-engineered solutions to environmental problems has become far more readily acceptable and widely understood. However there remains some uncertainty amongst practitioners regarding how and where the microscopic, functional level fits into the macroscopic, practical applications. It is precisely this gap which the book sets out to fill. Dividing the topic into logical strands covering pollution, waste and manufacturing, the book examines the potential for biotechnological interventions and current industrial practice, with the underpinning microbial techniques and methods described, in context, against this background. Each chapter is supported by located case studies from a range of industries and countries to provide readers with an overview of the range of applications for biotechnology. Essential reading for undergraduates and Masters students taking modules in Biotechnology or Pollution Control as part of Environmental Science, Environmental Management or Environmental Biology programmes. It is also suitable for professionals involved with water, waste management and pollution control.

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This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins with an overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections. Of high interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, pharmaceutists and those working in the pharmaceutical industry.

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The second volume in a new series dedicated to protein degradation, this book discusses the mechanism and cellular functions of targeted protein breakdown via the ubiquitin pathway. Drawing on the combined knowledge of the world's leading protein degradation experts, this handy reference compiles information on the proteasome-mediated degradation steps of the ubiquitin pathway. In addition to proteasomal function and regulation, it also presents the latest results on novel members of the ubiquitin superfamily and their role in cellular regulation. Further volumes in the series cover the function of ubiquitin-protein ligases, and the roles of the ubiquitin pathway in regulating key cellular processes, as well as its pathophysiological disease states. Required reading for molecular biologists, cell biologists and physiologists with an interest in protein degradation.

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This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease. The editors and authors represent unmatched expertise, comprising virtually all the top scientists in the field, including the pioneers of protein degradation research. From the contents: * Ubiquitin and cancer * Ubiquitin and liver cancer * Muscle atrophy * Aggresomes and human disease * Parkin and neurodegeneration * Chronic neurodegenerative diseases * Parkinson's disease * Ubiquitin and viruses * Druggability of the ubiquitin-proteasome system Required reading for molecular and cell biologists, as well as physiologists with an interest in the topic.

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The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required reading for molecular biologists, cell biologists and physiologists with an interest in the topic.

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This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance. A solid introduction to toxin structure and functions, as well as a valuable source of methodology for researchers in molecular biology, pharmacology and experimental medicine.

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With its focus on a completely novel class of pharmaceuticals, this book collates the hitherto scarce literature about DNA drug formulation keenly desired by biotechnologists, molecular biologists and pharmacists, as well as those working in the biotechnological and pharmaceutical industries. As such, this volume presents a wide range of gene delivery systems needed for different therapeutic applications. It fills the gap between research and clinical trials and describes pharmaceutical fundamentals for the development of efficient DNA pharmaceuticals.

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