Скачать книгу

405

      419  406

      420  407

      421  408

      422  409

      423  410

      424 411

      425 412

      426 413

      427 414

      428  415

      429  416

      430  417

      431  418

      432  419

      433  420

      434  421

      435  422

      436  423

      437  424

      438  425

      439  426

      440  427

      441  428

      442  429

      443  430

      444  431

      445  432

      446  433

      447  434

      448  435

      449  436

      450  437

      451  438

      452  439

      453  440

      454 441

      455 442

      456 443

      457 444

      458 445

      459 446

      460 447

      461 448

      462  449

      463  450

      464  451

      465  452

      466  453

      467  454

      468  455

      469  456

      470  457

      471  458

      472  459

      473  460

      474  461

      475  462

      476  463

      477  464

      478  465

      479  466

      480  467

      481  468

      482  469

      483 470

      484 471

      485 472

      486 473

      487 474

      488 475

      489 476

      490  477

      491  478

      492  479

      493  480

      494  481

      495  482

      496  483

      497  484

      498  485

      499  486

       This book is dedicated to my family:

       My late parents, Gopinath and Ichhamoni, for their gift of life, love, and living examples

       My wife, Jharana, for her life-long friendship, love, and support as well as for her patience and understanding of the long hours I spent at home on planning, writing, and editing this book

       My children, Meghamala, Sudhir, Subir, and their spouses, for their love and care

       My granddaughter, Naomi, and my grandson, Jonah, for their unconditional love, faith, and trust in me

      Saura C. Sahu, PhD

      Columbia, MD

      August 2021

      A biomarker is a measurable substance, found in body fluids or tissues as a result of exposure, infection, and/or disease, and it can be used for clinical practice. Genomics and epigenomics are modern scientific developments of the twenty-first century. They regulate gene expressions and play important roles in a wide range of human diseases, including cancer. The microRNAs are an important component of the molecular mechanisms of disease processes. Therefore they demonstrate potential for serving as biomarkers.

      It is my sincere hope that the up-to-date information presented in this monograph will serve as a stimulus to investigators interested in genomic and epigenomic biomarkers research.

      The importance of research on genomic and epigenomic biomarkers is evidenced by the growing number of contributions published each year. It becomes increasingly clear that developments in this field are moving so rapidly that new means are needed to report the status of ongoing research activities. The contributions presented in this monograph represent a collaborative effort by international experts in this emerging field of science.

      The main purpose of this book is to assemble up-to-date, state-of-the-art information on genomic and epigenomic biomarkers presented by internationally recognized experts in a single edition. I sincerely hope that this book will provide an authoritative source of current information on biomarkers research and will prove useful to the scientists interested in this scientific discipline throughout the world. Moreover, it should be of interest to a variety of other scientific disciplines such as toxicology, medicine, and pharmacology, as well as to drug and food sciences.

       Saura C. Sahu, PhD

      Columbia, MD

      I am indebted to the internationally recognized experts who shared my enthusiasm for this field of science and contributed generously to this book. They were selected from academia, industry, and government for their expertise in their own areas of research. Their

Скачать книгу