Genomic and Epigenomic Biomarkers of Toxicology and Disease - Группа авторов

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       This book is dedicated to my family:

       My late parents, Gopinath and Ichhamoni, for their gift of life, love, and living examples

       My wife, Jharana, for her life-long friendship, love, and support as well as for her patience and understanding of the long hours I spent at home on planning, writing, and editing this book

       My children, Meghamala, Sudhir, Subir, and their spouses, for their love and care

       My granddaughter, Naomi, and my grandson, Jonah, for their unconditional love, faith, and trust in me

      Saura C. Sahu, PhD

      Columbia, MD

      August 2021

      A biomarker is a measurable substance, found in body fluids or tissues as a result of exposure, infection, and/or disease, and it can be used for clinical practice. Genomics and epigenomics are modern scientific developments of the twenty-first century. They regulate gene expressions and play important roles in a wide range of human diseases, including cancer. The microRNAs are an important component of the molecular mechanisms of disease processes. Therefore they demonstrate potential for serving as biomarkers.

      It is my sincere hope that the up-to-date information presented in this monograph will serve as a stimulus to investigators interested in genomic and epigenomic biomarkers research.

      The importance of research on genomic and epigenomic biomarkers is evidenced by the growing number of contributions published each year. It becomes increasingly clear that developments in this field are moving so rapidly that new means are needed to report the status of ongoing research activities. The contributions presented in this monograph represent a collaborative effort by international experts in this emerging field of science.

      The main purpose of this book is to assemble up-to-date, state-of-the-art information on genomic and epigenomic biomarkers presented by internationally recognized experts in a single edition. I sincerely hope that this book will provide an authoritative source of current information on biomarkers research and will prove useful to the scientists interested in this scientific discipline throughout the world. Moreover, it should be of interest to a variety of other scientific disciplines such as toxicology, medicine, and pharmacology, as well as to drug and food sciences.

       Saura C. Sahu, PhD

      Columbia, MD

      I am indebted to the internationally recognized experts who shared my enthusiasm for this field of science and contributed generously to this book. They were selected from academia, industry, and government for their expertise in their own areas of research. Their

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