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      Clinical and Therapeutic Actions

       Edited by

       Saura C. Sahu

       Formerly of Center for Food Safety and Applied Nutrition,US Food and Drug Administration,MD, USA

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      The right of Saura C. Sahu to be identified as the author of the editorial material in this work has been asserted in accordance with law.

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      A catalogue record for this book is available from the Library of Congress

      Hardback ISBN: 9781119807674; ePub ISBN: 9781119807698; ePDF ISBN: 9781119807681;

      Obook ISBN: 9781119807704

      Cover image: © Ali Kahfi/Getty Images

      Cover design by Wiley

      Set in 9.5/12.5pt STIXTwoText by Integra Software Services Pvt. Ltd, Pondicherry, India

      1  Cover

      2  Title page

      3  Copyright

      4  Dedication

      5  Preface

      6  Acknowledgements

      7  List of Contributors

      8  1 Genomic and Epigenomic Biomarkers for Predictive Toxicity and Disease

      9  2 MicroRNAs as Non-invasive Biomarkers of Toxicity and Chemical Hazard: Genomic and Epigenomic Biomarkers of Toxicology and Disease

      10  3 EV (Extracellular Vesicle)-associated miRNAs as Biomarkers of Toxicity

      11  4 Circulating miRNAs as Biomarkers of Toxic Heavy Metal Exposure

      12  5 MicroRNA Biomarkers of Malignant Mesothelioma

      13  6 Role of Non-coding RNAs in Innate Immune Responses Perturbed by Environmental Arsenic Exposure

      14  7 Transcriptomics: Applications in Toxicology and Medicine

      15  8 Network Biology for Biomarker Discovery and Therapy in Cancer

      16  9 Epigenetic Biomarkers: Link to Maternal Exposure and Offspring Health Outcomes

      17  10 The Role of Dynamic Epigenetic Changes in Modulating Homeostasis after Exposure to Low-dose Environmental Chemicals

      18  11 Emerging Non-invasive Molecular Biomarkers for Early Cancer Detection

      19  12 Aberrant DNA Methylation of Tumor Suppressor Genes and Oncogenes as Cancer Biomarkers

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