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      4.4.1 Biological Conversion

      A wide variety of microorganisms such as microalgae, fungi, and bacteria have been used for glycerol transformation by aerobic and anaerobic metabolism. The biological conversion was carried out in large bio-reactors according to the demand of microorganisms. The key product of anaerobic fermentation of glycerol using bacteria is 1,3-propanediol (PDO). In addition to PDO, co-products such as formate, lactic acid, succinic acid, butyric acid, acetic acid, butanol, 2,3-butanediol, acetone, ethanol, and H2 are also formed [19]. The fermentation of glycerol using microorganisms produces lactic acid, eicosapentaenoic acid (EPA), polyhydroxyalkanoates (PHA), citric acid, hydrogen, etc. The biological conversion is the efficient pathway for glycerol transformation. Though, some limitations such as low product yield, slow kinetics, low selectivity, and low reusability limit their uses.

      4.4.2 Thermochemical Conversion

      Several solid acid catalysts such as metal oxide (A12O3), zeolite H-ZSM-5, metal sulfide (CdS), immobilized liquid acid (e.g. HF/AlCl3), heteropoly acid (e.g. H3PW12O40), solid superacid (SO42–/ZrO2), natural clay, etc., have been tested for different catalytic processes [20]. None of the above catalysts have shown full potential for glycerol valorization on large scale. Carbon-based materials have a large potential to be used as supports for many active metals as well as catalysts after modification owing to their large surface area, stability in both acidic and basic solutions, functional properties, and desirable acidic or basic sites. The carbon has been used as a support for various metals such as Ru, Pt, Re, Cu, etc. for the glycerol conversion into useful products [21]. In some processes, the carbon-based catalyst with acidic sites has received tremendous interest compared to homogeneous catalysts. This is attributed to its stability, efficiency, viability, and sustainability. Furthermore, carbon catalysts can be recycled numerous times without losing their activity. In particular, carbon-based sulfonated catalysts (CBSCs) are a rapidly growing field for glycerol valorization due to their easy recovery, recyclability, long-term activity, and stability.

Schematic illustration of roadmap of selected glycerol valorization reactions.

      The basic principles, mechanisms and role of different carbon-based catalysts for different catalytic routes have been explained in the next section.

       4.4.2.1 Hydrogenolysis of Glycerol

      Hydrogenolysis is defined as a catalytic route that involves the selective scission of carbon–carbon or carbon–heteroatom bonds in an organic compound by reaction with molecular hydrogen. Hydrogenolysis of biomass-derived compounds comprises a promising route to several industrially important chemicals, such as hydrocarbons, by complete deoxygenation, and polyols by lysis and/or partial deoxygenation of the carbon chain [9]. Owing to the increasing availability and falling prices in the market, glycerol is now considered an important substrate and much of the focus has now been diverted towards its transformation via this route. Several chemical compounds such as 1,2-PD (1,2-propanediol), ethylene glycol (EG), 1,3-PD (1,3-propanediol), propylene, 1-propanol, etc. can be synthesized by selective glycerol hydrogenolysis using a suitable metallic catalyst. It can be considered as another possible path to enhance the productivity of biodiesel industries since the products of this route are commercially produced either from non-renewable resources or through biological routes using high-cost microorganisms.

Schematic illustration of structure of biomass-derived CBSC.

      Researchers explored both homogeneous and heterogeneous catalytic routes for the glycerol hydrogenolysis to improve the selectivity and yield of desirable products 1,2-PD, 1,3-PD, and EG. In homogeneous catalysis, several homogeneous complexes of metals (Pd, Rh, Ru,) have been explored as a catalyst in the presence of a suitable solvent. However, this homogeneous catalytic route is not economically and environmentally attractive because the catalysts are irrecoverable and nonrecyclable. Moreover, the use of toxic solvents causes this process to become environmentally unfriendly [13, 14]. The heterogeneous catalytic approach of using solid catalysts can overcome these limitations of homogenous catalysis.

      1,3-PD is a vital industrial chemical consumed as an intermediate or solvent in pharmaceutical, textile, and food industries. It has extensive applications in the polymer industry for the production of polyurethane and polytrimethylene terephthalate. The large-scale production of 1,3-PD occurs by glycerol fermentation using expensive genetically modified microorganisms. 1,2-PD is a chief chemical that is used extensively in the production of polymers, pharmaceuticals, plastics, and transportation fuel. It is also used as an antifreeze agent, solvent, hydraulic fluid, and used for cosmetics, and food production industries. 1,2-PD is commercially prepared from the propylene oxide through the hydration method. Propylene oxide is derived from propylene which is a product of fossil fuels. So, the generation of 1,2-PD from a renewable resource is attractive [22].

      Generally, the availability of Bronsted acid sites on the catalyst is required to synthesize the 1,3-PD through

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