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As this injury heals during the ensuring days, the injured tissue sloughs off and an ulcer develops at the site as part of the body's attempt to clear injured tissue. In most cases, this does not result in problems and these ulcerations will heal without symptoms to the patient. In some instances though, as the ulcer develops, it can erode into a vessel, resulting in sudden onset of GI bleeding. This complication typically occurs 2–7 days after the procedure. Deeper tissue injury can also result in serosal inflammation (resulting in post‐polypectomy electrocoagulation syndrome characterized by focal peritoneal pain) or even transmural injury with perforation [15, 16]. These two complications are of particular concern with the use of cautery in the cecum where the colon wall is the thinnest. These complications are uncommon yet great care must be taken to minimize injury to adjacent tissue. The depth and degree of injury is dependent on the power used (watts) and duration of current (how long the foot peddle is pressed). In the cecum, cold techniques (biopsy or snare as below) are preferable, but if cautery is needed, a lower setting such as 12–14 watts could be used [13].

Image described by caption.

      (Contributed with permission from Advanced Digestive Endoscopy: Comprehensive Atlas of High‐Resolution Endoscopy and Narrowband Imaging. Edited by J. Cohen. Blackwell Publishing. 2007: pp. 269, 271, 295, 304, 306, 307, 311, 312.)

Photo depicts snare polypectomy.

      For flat polyps that are difficult to grasp, the mucosal layer can be lifted using an endoscopy needle to inject saline (or other agent) to create a fluid cushion between the mucosa and the deeper layers [17]. This is similar to the endoscopic mucosal resection (EMR) technique typically used on polyps larger than 20 mm. EMR technique will be covered in a later chapter.

      The use of any monopolar device (coagulation grasper, hot biopsy cable, snare, and argon plasma coagulation) all work by sending a current through the patient and need to be used with great care in patients with pacemakers or defibrillators, as the current can cause these devices to malfunction or discharge (defibrillator), resulting in harm to the patient or injury to the endoscopist. If monopolar cautery is to be used, patients with a defibrillator or who are pacemaker dependent should have cardiac monitoring and the defibrillator should be turned off (a magnet placed over the device) while cautery is in use. For pacemakers only in patients who are not dependent, turning the pacemaker off is typically not needed. Older pacemakers may need to be interrogated by a specialist following endoscopy to ensure proper functioning; however, for most pacers/defibrillators placed in the past 15 years or so are insulated well enough that this is generally not recommended. As discussed in the section “Preparation,” cautery should be avoided in an unprepared or poorly prepared colon due to the risk of igniting the flammable gases present in the colon.

      Complication management

      As with any procedure, colonoscopy has risks. These range from oversedation, hypoxia, and other airway or hemodynamic problems to complications more directly related to the scope itself, such as bleeding or perforation. Sedation complications and endoscopic hemostasis will be discussed elsewhere in this book. This section will address the management of colonic perforation.

Schematic illustration of looping causing perforation.

      (Copyrighted and used with permission of Mayo Foundation for Medical Education and Research.)

      The key to managing colonic perforation is early recognition. Often if the perforation is caused by the scope's tip, the peritoneal cavity, organs, or serosa will be readily visible to the camera lens. When perforation occurs as a result of looping, the defect and fresh blood will commonly be identified during withdrawal. Commonly with perforations, the patient will develop increased distention of the abdomen due to free air or worsening abdominal pain either during the procedure or in recovery. If perforation is at all suspected, immediate evaluation with imaging such as an abdominal CT scan is indicated to evaluate for free peritoneal air. A CT scan can detect much smaller collections of free air than upright abdominal X‐rays and as such is preferred; however, if not available, upright abdominal X‐rays can help identify free abdominal air. If identified, immediate evaluation and likely intervention by a surgeon is required. Delay in intervention can lead to sepsis and even death. If perforation is identified during the endoscopic examination, immediate endoscopic closure is ideal followed by a single dose of broad‐spectrum antibiotic and overnight observation in the hospital for signs of peritonitis. Attempts at endoscopic closure of perforations using hemoclips or other closure devises will be discussed in Chapter 24. Endoscopic

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