Drug Transporters - Группа авторов

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Institute of Clinical Pharmacology, University of Tuebingen, Stuttgart, Germany; Cluster of Excellence iFIT (EXC2180) “Image‐Guided and Functionally Instructed Tumor Therapies”, University of Tuebingen, Tuebingen, Germany

      Gregory T. Knipp,Department Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, IN, USA

      Megan L. Koleske,Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA

      Deanna L. Kroetz,Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA

      Nisha V. Kwatra,Division of Inflammation and Immune Pharmacology, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA

      Yurong Lai,Drug Metabolism, Gilead Sciences Inc., Foster City, CA, USA

      Xiaomin Liang,Drug Metabolism, Gilead Sciences Inc., Foster City, CA, USA

      Sabrina Lusvarghi,Laboratory of Cell Biology, Transport Biochemistry Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

      Kazuya Maeda,Laboratory of Pharmaceutics, Kitasato University School of Pharmacy, Minato‐ku, Tokyo, Japan

      Qingcheng Mao,Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA

      Yusuke Masuo,Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan

      Marilyn E. Morris,Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA

      Stephanie Mowery,Department Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, IN, USA; Novo Nordisk Research Center, Indianapolis. Inc., Biology Indianapolis, IN, USA

      William A. Murphy,Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

      Sibylle Neuhoff,Simcyp Division, Certara UK Ltd., Sheffield, UK

      Anne T. Nies,Dr. Margarete Fischer‐Bosch Institute of Clinical Pharmacology, University of Tuebingen, Stuttgart, Germany; Cluster of Excellence iFIT (EXC2180) “Image‐Guided and Functionally Instructed Tumor Therapies,” University of Tuebingen, Tuebingen, Germany

      Sanjay K. Nigam,Departments of Pediatrics and Medicine, University of California, San Diego, CA, USA

      Stefan Oswald,Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany

      Antonio López Quiñones,Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA

      Robert W. Robey,Laboratory of Cell Biology, Multidrug Resistance Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

      Patrick T. Ronaldson,Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA

      Amin Rostami‐Hodjegan,Simcyp Division, Certara UK Ltd., Sheffield, UK; Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, UK

      Andaleeb Sajid,Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

      Vishal Sangha,Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada

      Noora Sjöstedt,Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

      Tore B. Stage,Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark

      Yuichi Sugiyama,Laboratory of Quantitative Systems Pharmacokinetics/Pharmacodynamics, Faculty of Pharmaceutical Sciences, Josai International University, Chiyoda‐ku, Tokyo, Japan

      Peter W. Swaan,Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, USA

      Douglas H. Sweet,School of Pharmacy, Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA, USA

      Rommel G. Tirona,Departments of Physiology & Pharmacology and Medicine, The University of Western Ontario, London, Ontario, Canada

      Jashvant D. Unadkat,Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA

      Manthena V. S. Varma,ADME Sciences, Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research & Development, Pfizer Inc, Groton, CT, USA

      Joanne Wang,Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA

      Erica I. Williams,Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA

      Victoria Woo,Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA

      Guofeng You,Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA

      Jinghui Zhang,Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA

      Qing Zhang,Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA, USA

      The contributions by the leaders in the field of drug transport to the 1st and the 2nd editions of Drug Transporters have helped to secure a special role for this book in the education of students, fellows, and industrial practitioners in the pharmaceutical and biomedical sciences. The 2nd edition was published 8 years ago. Since then, there has been significant advances in the field including in‐depth understanding of membrane transporters in pediatric pharmacotherapy, new insights into the impact of these transporters on drug efficacy/safety, development of more sophisticated model systems and sensitive assay methods for studying drug transport in vitro and in vivo, and knowledge of transporters as drug targets for diseases. Therefore, it has become clear that a 3rd edition that serves to capture current advances in the field is both timely and necessary.

      The new (3rd) edition will preserve the same basic format as that of the previous two editions: the first half of the book provides an overview of the relevant drug transporters useful for both beginning and experienced scientists and researchers. The second half of the book presents the principles of drug transport and associated techniques in sufficient detail to enable nonspecialist readers to understand them. Such readers include graduate students in the pharmacological or physiological sciences and academic or industrial scientists in related fields of study. There are 25 chapters in the 3rd edition as compared with 23 chapters in the 2nd edition. This represents an update of most of the chapters, significant expansion of others, removal of chapters for which content has been incorporated into other chapters, and addition of four new chapters. New chapters include in vitro–in vivo scale‐up of drug transport

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