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Demystifies the largest volume manmade synthetic polymer by distillingthe fundamentals of what polyethylene is, how it's made and processed,and what happens to it after its useful life is over. Endorsement for Introduction to Industrial Polyethylene «I found this to be a straightforward, easy-to-read, and useful introductory text on polyethylene, which will be helpful for chemists, engineers, and students who need to learn more about this complex topic. The author is a senior polyethylene specialist and I believe we can all benefit from his distillation of knowledge and insight to quickly grasp the key learnings.» —R.E. King III; Ciba Corporation (part of the BASF group) Jargon used in industrial polyethylene technology can often be bewildering to newcomers. Introduction to Industrial Polyethylene educates readers on terminology commonly used in the industry and demystifies the chemistry of catalysts and cocatalysts employed in the manufacture of polyethylene. This concise primer reviews the history of polyethylene and introduces basic features and nomenclatures for this versatile polymer. Catalysts and cocatalysts crucial to the production of polyethylene are discussed in the first few chapters. Latter chapters provide an introduction to the processes used to manufacture polyethylene and discuss matters related to downstream applications of polyethylene such as rheology, additives, environmental issues, etc. Providing industrial chemists and engineers a valuable reference tool that covers fundamental features of polyethylene technology, Introduction to Industrial Polyethylene: Identifies the fundamental types of polyethylene and how they differ. Lists markets, key fabrication methods, and the major producers of polyethylene. Provides biodegradable alternatives to polyethylene. Describes the processes used in the manufacture of polyethylene. Includes a thorough glossary, providing definitions of acronyms and abbreviations and also defines terms commonly used in discussions of production and properties of polyethylene. Concludes with the future of industrial polyethylene.

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The authoritative guide on protein purification—now completely updated and revised Since the Second Edition of Protein Purification was published in 1998, the sequencing of the human genome and other developments in bioscience have dramatically changed the landscape of protein research. This new edition addresses these developments, featuring a wealth of new topics and several chapters rewritten from scratch. Leading experts in the field cover all major biochemical separation methods for proteins in use today, providing professionals in biochemistry, organic chemistry, and analytical chemistry with quick access to the latest techniques. Entirely new or thoroughly revised content includes: High-resolution reversed-phase liquid chromatography Electrophoresis in gels Conventional isoelectric focusing in gel slabs and capillaries and immobilized pH gradients Affinity ligands from chemical and biological combinatorial libraries Membrane separations Refolding of inclusion body proteins from E. coli Purification of PEGylated proteins High throughput screening techniques in protein purification The history of protein chromatography

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Explore polymer rheology from an industrial standpoint Presenting state-of-the-art polymer rheology as observed by well-recognized authors, Applied Polymer Rheology: Polymeric Fluids with Industrial Applications is designed to help readers understand the relationship between molecular structure and the flow behavior of polymers. In particular, it focuses on polymeric systems that elicit special attention from industry. Providing a comprehensive overview of the rheological characteristics of polymeric fluids, the book bridges the gap between theory and practice/application, enabling readers to see the connection between molecular structure and the behavior of the polymers studied. Beginning with a discussion of the properties, processability, and processing aids of specific polymers, later chapters examine filled polymers and composites, and the theoretical framework upon which their analysis is based. Various systems containing microstructure are presented subsequently, with the final chapter introducing paste extrusion of polytetrafluoroethylene paste. An invaluable reference guide that covers the literature and vast array of technical approaches to polymer rheology, Applied Polymer Rheology's coverage of polymeric fluids of interest to industry make it an essential resource for plastics, polymer, and chemical engineers, materials scientists, polymer chemists, and polymer physicists to use when interpreting findings and planning experiments.

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Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the «right» drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development. Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical—pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment—this unique resource encourages integrated thinking in drug discovery. The contributors to this volume: Cover drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, stability, drug formulation, preclinical safety assessment, toxicology, and toxicokinetics Address developability issues that challenge pharma companies, moving beyond isolated experimental results Reveal connections between the key scientific areas that are critical for successful drug discovery and development Inspire forward-thinking strategies and decision-making processes in preclinical evaluation to maximize the potential of drug candidates to progress through development efficiently and meet the increasing demands of the marketplace Evaluation of Drug Candidates for Preclinical Development serves as an introductory reference for those new to the pharmaceutical industry and drug discovery in particular. It is especially well suited for scientists and management teams in small- to mid-sized pharmaceutical companies, as well as academic researchers and graduate students concerned with the practical aspects related to the evaluation of drug developability.

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This volume tells the story of major organizational change efforts at one municipal youth-serving organization to better support healthy youth development system wide. Presenting the viewpoints of young people, frontline staff, supervisors, managers, and the director, it reviews how the organization developed and transformed. Each article then describes the different strategies and tactics used to support organizational transformation. Learn: How a youth work professional development strategy ended up as an organizational development and change strategy How the partnership with a university expanded to include community-based research and evaluation to support youth program development and improvement within the organization. How youth advice structures can support high-quality youth programming and, by extension, improvements in organizational supports for quality youth programs How partnerships with other organizations supported ongoing adaptation of the organization to better address youth needs This is the 139th volume of New Directions for Youth Development, the Jossey-Bass quarterly report series dedicated to bringing together everyone concerned with helping young people, including scholars, practitioners, and people from different disciplines and professions.

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Take an in-depth look at the difficulty in gaining traction at the institutional level in improving student retention and degree completion rates—especially at larger four year institutions where size, complexity, and multiplicity of structures and processes present particular challenges. This volume offers a way for institutional leaders to better focus their time, energy, and resources in their retention effort by framing the way they think about it using the 4 Ps of retention strategy: profile, progress, process, and promise. This simple framework challenges long-standing, traditional assumptions about student retention that can distract and dilute institutional efforts, and helps keep those efforts sharply and singularly focused on improving retention and degree completion outcomes. This is the 161st volume of this Jossey-Bass series. Addressed to higher education decision makers on all kinds of campuses, New Directions for Higher Education provides timely information and authoritative advice about major issues and administrative problems confronting every institution.

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This issue of New Directions for Evaluation (NDE) marks a milestone: the 25th anniversary of the American Evaluation Association (AEA). NDE is an official publication of AEA and has been a crucial means for the Association to foster and promote the professionalization of evaluation through thematic discussions of theory and practice in evaluation. NDE was first published in 1978 under the name New Directions for Program Evaluation, although the title became New Directions for Evaluation in 1995 in acknowledgement of the broader scope of evaluation.

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Since their inception, America’s community colleges have undergone continuous change. They must, because their mission is to provide learning vital for those who face local as well as global transformations, and that requires vigilant, vigorous commitment. This volume contains insights from men and women who have led the thinking and practice in these colleges to current historical heights. They were asked to forecast solutions to today's most critical problems as well as to identify opportunities that will likely engage tomorrow's community college leaders. In addition, a prevailing university authority was asked to review the support system traditionally relied upon to provide expertise to faculty and administrators. «Presidents and Analysts Discuss Contemporary Issues» collects decades of experience from extraordinary leaders and places that wisdom in readers' hands. This is the 156th volume of this Jossey-Bass quarterly report series. Essential to the professional libraries of presidents, vice presidents, deans, and other leaders in today's open-door institutions, New Directions for Community Colleges provides expert guidance in meeting the challenges of their distinctive and expanding educational mission.

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The numerical simulation of manufacturing processes and of their mechanical consequences is of growing interest in industry. However, such simulations need the modeling of couplings between several physical phenomena such as heat transfer, material transformations and solid or fluid mechanics, as well as to be adapted to numerical methodologies. This book gathers a state of the art on how to simulate industrial processes, what data are needed and what numerical simulation can bring. Assembling processes such as welding and friction stir welding, material removal processes, elaboration processes of composite structures, sintering processes, surface-finishing techniques, and thermo-chemical treatments are investigated. This book is the work of a group of researchers who have been working together in this field for more than 12 years. It should prove useful for both those working in industry and those studying the numerical methods applied to multiphysics problems encountered in manufacturing processes.

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Introduces the latest innovations in thermoforming materials, processes, and applications Advanced Thermoforming brings readers fully up to date with the latest standards, processes, materials, and applications in the field. From forming to filling to sealing processes, the author explains everything that can now be accomplished using the most advanced thermoforming technologies available. Moreover, readers learn how to fully leverage these technologies in order to design and manufacture products that meet all specifications at minimum cost and maximum efficiency. Emphasizing the application of advanced thermoforming for the production of technical parts and packaging, the book: Guides readers through all facets of development, design, and machine and mold technology Recommends new technologies that offer higher productivity, better quality, and lower costs Describes common raw materials used in thermoforming, including how specific materials affect the production process Explains the proper handling of semi-finished products and formed parts Sets forth the basic principles of extrusion, an essential process underlying thermoforming Introduces the latest software techniques to simulate the thermoforming of new products Throughout the book, readers learn about the latest innovations in thermoforming, from thermoformed automobile body parts to fully automated packaging assembly lines. The author offers valuable content from his interviews with leading industrial thermoformers, sharing insights and tips from their years of hands-on experience with readers. With Advanced Thermoforming as their guide, polymer and plastics engineering professionals and students can now explore and exploit the full range of possibilities that thermoforming technology offers.

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