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One of the exciting aspects of being involved in the field of molecular biology is the ever-accelerating rate of progress, both in the development of new methodologies and the practical applications of these methodologies. This popular textbook has been completely revised and updated to provide a comprehensive overview and to reflect key developments in this rapidly expanding area. Chapters on the impact of molecular biology in the development of biotechnology have been fully updated and include the applications of molecular biology in the areas of diagnostics, biosensors and biomarkers, therapeutics, agricultural biotechnology and vaccines. The first six chapters deal with the technology used in current molecular biology and biotechnology. These primarily deal with core nucleic acid techniques, genomics, proteomics and recombinant protein production. Further chapters address major advances in the applications of molecular biotechnology. By presenting information in an easily assimilated form, this book makes an ideal undergraduate text. Molecular Biology and Biotechnology 6th Edition will be of particular interest to students of biology and chemistry, as well as to postgraduates and other scientific workers who need a sound introduction to this ever rapidly advancing and expanding area.

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Two recent initiatives from the EU, namely the Bologna Process and the Lisbon Agenda are likely to have a major influence on European Higher Education. It seems unlikely that traditional teaching approaches, which supported the elitist system of the past, will promote the mobility, widened participation and culture of 'life-long learning' that will provide the foundations for a future knowledge-based economy. There is therefore a clear need to seek new approaches to support the changes which will inevitably occur. The European Chemistry Thematic Network (ECTN) is a network of some 160 university chemistry departments from throughout the EU as well as a number of National Chemical Societies (including the RSC) which provides a discussion forum for all aspects of higher education in chemistry. This handbook is a result of one of their working groups, who identified and collated good practice with respect to innovative methods in Higher Level Chemistry Education. It provides a comprehensive overview of innovations in university chemistry teaching from a broad European perspective. The generation of this book through a European Network, with major national chemical societies and a large number of chemistry departments as members make the book unique. The wide variety of scholars who have contributed to the book, make it interesting and invaluable reading for both new and experienced chemistry lecturers throughout the EU and beyond. The book is aimed at chemistry education at universities and other higher level institutions and at all academic staff and anyone interested in the teaching of chemistry at the tertiary level. Although newly appointed teaching staff are a clear target for the book, the innovative aspects of the topics covered are likely to prove interesting to all committed chemistry lecturers.

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The exceptional mechanical, optical, surface and biocompatibility properties of nanodiamond have gained it much interest. Exhibiting the outstanding bulk properties of diamond at the nanoscale in the form of a film or small particle makes it an inexpensive alternative for many applications. Nanodiamond is the first comprehensive book on the subject. The book reviews the state of the art of nanodiamond films and particles covering the fundamentals of growth, purification and spectroscopy and some of its diverse applications such as MEMS, drug delivery and biomarkers and biosensing. Specific chapters include the theory of nanodiamond, diamond nucleation, low temperature growth, diamond nanowires, electrochemistry of nanodiamond, nanodiamond flexible implants, and cell labelling with nanodiamond particles. Edited by a leading expert in nanodiamonds, this is the perfect resource for those new to, and active in, nanodiamond research and those interested in its applications.

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While it is not difficult to find data in many cases, what advice can you get on the quality of the data retrieved? Chemical Information for Chemists could help with this problem and more. This book is a chemical information book aimed specifically at practicing chemists. Written and edited by experts in the field, it is ideal for chemists who lack a chemical information professional able to teach basic and intermediate techniques in retrieving and evaluating information using the unique entry points of the chemical literature, including structure, formula, substructure, and sequence. Aimed at students on undergraduate and graduate courses, it could also be a useful guide to new information specialists who are facing the challenging diversity of chemical literature.

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Food Scientists have been teaching the subject in the same way for the past fifty years. This book therefore aims to modernise the coverage of the subject, bringing it in line with the recent and extensive developments in Materials Science; in particular, the field of supramolecular chemistry of food components has been generally overlooked in textbooks. Edible Nanostructures will summarise developments in the areas of protein aggregation and gelation, starch crystallography, emulsions, and fat crystal network nanostructure and microstructure, addressing their functionalities in food. Each chapter offers both the qualitative view and a basic quantitative treatment of the area, including basic models used to describe structure and its relationship to functionality, if they exist. This is the first book on nanostructures in foods, and is suitable as a textbook for undergraduate students in Chemistry, Physics and Food Science.

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The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

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John Pilcher’s appointment as HM Ambassador to Japan in 1967, three years after the widely acclaimed Tokyo Olympics, was both judicious and enlightened. His role was to be that of a bridge-builder between Japan and Britain following the early post-war years of disenchantment, distrust and detachment that had earlier marked the relationship between the two countries. He brought to his role a particular understanding of Japanese civilization and a critical analysis of Japanese attitudes and way of life. Before the war he had had the good fortune to spend time as a language student in Kyoto. There he came to appreciate Japanese culture at its best but as a junior consular official he also came to see other less attractive aspects of Japan. In this volume Sir Hugh Cortazzi who was to follow in John Pilcher’s footsteps, has compiled the defining reports to Whitehall from Pilcher’s time and as such they offer a valuable record of Japan’s progress at this important point in her post-war history, as well as providing unique insights into the activities, hopes and expectations of the British government in her dealings with Japan. The collection (including essays and writings from his private papers) which has hitherto remained largely unknown or inaccessible to most researchers, provides a platform for John Pilcher as a writer and distinguished scholar-diplomat.

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Published in association with the Japan Society and containing 57 essays, this ninth volume in the series continues to celebrate the life and work of the men and women, both British and Japanese, who over time played an interesting and significant role in a wide variety of different spheres relating to the history of Anglo-Japanese relations and deserve to be recorded and remembered. Read together they give a picture, even if inevitably a partial one, of important facets of modern history and Anglo-Japanese institutions. They shed light on a number of controversial issues as well as illuminate past successes and failures. Structured thematically in four Parts – Japan in Britain, Britain in Japan, Scholars and Writers, Politicians and Officials – the highlights in this volume include: The Great Japan Exhibition, 1981-82; Japanese Gardens and the Japanese Garden Society in the UK; Cricket in Late Edo and Meiji Japan; Norman Macrae, pioneering journalist of The Economist; Arthur Balfour – managing the emergence of Japan as a Great Power; Michio Morishima, an economist ‘made in Japan’; Margaret Thatcher – a pragmatist who radically improved Britain’s image in Japan.

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Comprehensive Review in Vascular and Endovascular Medicine provides a primer for clinicians from various disciplines who care for patients with vascular disease. Written by a multidisciplinary panel of nationally and internationally recognized experts, this book incorporates the latest information on medical, endovascular, and surgical therapies. Features include: an evidence-based approach that emphasizes landmark trials and guidelines; key points that summarize critical knowledge; video clips that highlight significant diagnostic findings and interventional approaches; case studies or board questions to help the reader integrate material. The text has been endorsed by the Society for Vascular Medicine and Vascular Interventional Advances.

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Transradial Access: Techniques for Diagnostic Angiography and Percutaneous Intervention offers a single source for both novice and experienced interventional cardiologists for safely and effectively performing transradial catheterization procedures. First described in 1989, the transradial approach for coronary angiography and percutaneous interventions has seen a constant and progressive increase around the world as a result of significantly reduced procedural complications, shorter hospital stays, increased patient satisfaction, and lower associated costs compared with the transfemoral approach.
Yet despite its apparent benefits, adoption of this technique in the United States has been slow, largely due to the increased technical aspects of entering a smaller artery, accessing the central circulation and engaging the coronary arteries from this approach. In addition, until recently the technique was not routinely taught in the majority of training programs. This book flattens that learning curve by highlighting the technical aspects of transradial diagnostic and interventional procedures, and includes detailed discussion of:
Normal vascular anatomy of the hand and arm Indications and contraindications for transradial access procedures Patient and catheter selection Tips and tricks for both beginner and advanced operators Procedural pitfalls and potential complications

Techniques are demonstrated in detail using both still images and video. Whether you are an experienced transfemoral operator who wants to refine and expand your technique or a new transradial operator looking to master the technique, this comprehensive text holds the key to mastering this revolutionary procedure.

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