The Principles and Practice of Antiaging Medicine for the Clinical Physician - Dr. Vincent C. Giampapa The River Publishers Series in Research and Business Chronicles: Biotechnology

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practice.

      Along with the use of these key biomarkers, an overall age-management program should include essential key anti-aging supplements12–30 to accomplish the key goals previously discussed. With the right balance of nutraceuticals, it is possible to markedly improve key modifiable biomarkers, as follows:

      1. Decreasing DNA damage rates.

      2. Increasing DNA repair rates.

      3. Improving immune function.

      4. Regulating the key concepts of the aging equation: the processes of glycation, methylation, oxidation and inflammation.

      This approach also helps balance the biorhythmic cycle and pattern of the autonomic nervous system and aids in regulating hormonal release patterns.

      Further improvement in the assimilation and use of basic food nutrients ingested with each meal can be accomplished as well by aiding the digestion with the right digestive enzymes and supplemental intestinal flora support.

      Improvement in the pH levels of both the extracellular matrices (“cellular soup”—that is, the fluid around the cells) and the intracellular matrix (the fluid within the cells) markedly enhances the biochemical efficiency of the cell machinery and improves the aging process at this microscopic level.

      Another main concept to keep in mind is the delivery of these supplements throughout the day: that is, a phased delivery system. The use of as many naturally occurring plant and enzymatic complexes as possible, rather than synthetic supplements, is also important. It will be made clearer later that the natural components in products are much more effective than synthetically manufactured or designed supplements.

      In summary, the overall effects of this nutraceutical approach are as follows:

      1. Improved gene expression31 (Diagrams III-14 and III-15).

      2. Improved quality of life.

      3. Improved modifiable biomarkers of aging.

      4. A noticeable effect and improvement in the overall physical signs of aging that plastic surgeons recognize.

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      Since the early 1990s, this strategy has been shown to be very successful in all patients who have been treated with this approach.

      It is, without question, time to realize that this information and these simple laboratory tests are at physicians’ disposal to improve the well-being of patients’ quality of life, as well as their overall physical appearances.

       References

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