Теломераза. Как сохранить молодость, укрепить здоровье и увеличить продолжительность жизни - Майкл Фоссел Доказательная медицина

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G.",Leonard Hayftick and the Limits of Ageing." Lancet 377, no. 9783 (2011): 2075.

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      На самом деле предел Хейфлика зависит от того, клетки какого типа мы рассматриваем. В случаях, приводимых здесь, речь идет о пределе Хейфлика для фибробластов – клеток, типичных для практически любого живого организма.

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      Hayflick, L. "When Does Aging Begin?” Research on Aging 6, no. 99 (1984): 103.

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      Takubo, K. etai "Telomere Lengths Are Characteristic in Each Human Individua l. "Experimental Gerontology 37, (2002): 523-31.

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      Эти основания, или нуклеотиды, являются генетическими «буквами», которыми записываются гены в наших хромосомах. В ДНК всего четыре «буквы» – Т, A, G и С, – но их достаточно, чтобы записать абсолютно все наши гены.

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      Takubo, К. et at. – "Telomere Lengths Are Characteristic in Each Human Individual." Experimental Gerontology 37,120021: 523-31.

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      Shetton, D.N. et al. “Microarray Analysis of Replicative Senescence." 939—45.

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      Shelton, D.N. et at. “Microarray Analysis of Replicative Senescence." 939—45.

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      Hayflick, L. “Intracellular Determinants of Cell Aging.” Mechanisms of Ageing Development 28 (1984): 177-85.

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      Hayflick, L. Cell aging. Chapter 2 in EisdorferC. (Ed). Annual Review of Gerontology and Geriatrics, Volume 1. Springer Publishing, 1980.

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      West, M.D. et.al. “Altered Expression of Plasminogen and Plasminogen Activator Inhibitor During Cellular Senescence.” Experimental Gerontology 31 (1996): 175—93.

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      Helton, D.N. et at. “Microarray Analysis of Replicative Senescence. ” 939—45.

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      Rogues, C.N., Boyer, J.C., Färber, R.A. “Microsatellite Mutation Rates Are Eguivalent in Normal and Telomerase-immortalized Human Fibroblasts. ” Cancer Research 61 (2001): 8405—07.

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      Килобаза – единица измерения длины ДНК или РНК В генетике равняется 1 тыс. нуклеотидов.

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      На самом деле даже у взрослых некоторые нейроны и мышечные клетки делятся, но очень редко.

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