LITMIR.BIZ

      “Hel-lo!”

      Here is the first surprise: Elihu Hoopes greets Margot Sharpe with such eager warmth, it’s as if he has known her for years. As if there is a profound emotional attachment between them.

      The second surprise: Elihu Hoopes himself, who is nothing like Margot Sharpe has expected.

      It is 9:07 A.M., October 17, 1965. The single defining moment of Margot Sharpe’s life as it will be the single defining moment of Margot Sharpe’s career.

      Purely coincidentally it is the eve of Margot Sharpe’s twenty-fourth birthday—(about which no one here in Darven Park, Pennsylvania, knows, for Margot has uprooted her midwestern life and cast it among strangers)—when she is introduced by Professor Milton Ferris to the amnesiac patient Elihu Hoopes as a student in Professor Ferris’s neuropsychology laboratory at the university. Margot is the youngest and most recent addition to the renowned “memory” laboratory; she has been accepted by Ferris as a first-year graduate student, out of numerous applicants, and she is dry-mouthed with anticipation. For weeks, she has been reading material pertinent to Project E.H.

      Yet, the amnesiac E.H. is so friendly, and so gentlemanly, Margot feels comforted at once.

      The man is unexpectedly tall—at least six feet two. He is straight-backed, vigorous. His skin exudes a warm glow and his eyes appear to be normal though Margot knows that the vision in his left eye is very poor. He is not at all the impaired individual Margot has expected to meet, who had to relearn a number of basic physical skills since the devastating injury to his brain just fifteen months before, when he was thirty-seven.

      Margot thinks that E.H. emanates an air of manly charisma—that mysterious quality to which we respond instinctively without being able to explain. He is even well dressed, preppy-style, in clean khakis, a long-sleeved linen shirt, oxblood moccasins with patterned cotton socks—in contrast to other patients at the Institute whom Margot has glimpsed lolling about in hospital gowns or rumpled civilian wear. She has been told that E.H. is a descendant of an old, distinguished Philadelphia family named Hoopes, onetime Quakers who were central to the Underground Railway in the years preceding the Civil War; E.H. has a large, extended family in the area, but no wife, children, parents.

      Elihu Hoopes is something of an artist, Margot has learned. He has sketchbooks, he keeps a journal. In his former lifetime he’d been a partner in a family-owned investment firm in Philadelphia but before that he’d been a student at Union Theological Seminary and a civil rights activist and supporter. Is it strange that Elihu Hoopes is unmarried, at nearly forty? Margot wonders if this somewhat patrician individual has had a history of relationships with women in which the women were found wanting, and cast aside—never guessing that his time for love, marriage, fathering children would come so abruptly to an end.

      Camping alone on an island in Lake George, New York, the previous summer, E.H. was infected by a particularly virulent strain of herpes simplex encephalitis, that usually manifests itself as a cold sore on a lip, and fades within a few days; in E.H.’s case, the viral infection traveled along his optic nerve and into his brain, resulting in a prolonged high fever that ravaged his memory.

      Unfortunately E.H. lingered too long before calling for help. Like a morbidly curious scientist he’d recorded his temperature in a notebook, in pencil—(the highest recorded reading was 103.1 degrees F)—before he’d collapsed.

      This was ironic: a macho self-destructiveness. Like the premature death of the painter George Bellows who’d been reluctant to leave his studio to get help, though stricken by appendicitis.

      In the vast Adirondack region there’d been no first-rate hospital, no adequate medical treatment for such a rare and catastrophic infection. By the time the delirious and convulsing man had been brought by ambulance to the Albany Medical Center Hospital where emergency surgery was performed to reduce the swelling in his brain it was already too late. Something essential had been destroyed in his brain, and the damage appears to be irreversible. (It is Milton Ferris’s hypothesis that the damaged region is the small seahorse-shaped structure called the hippocampus, located just above the brain stem and contiguous with the cerebral cortex, about which not much is yet known, but which seems to be essential for the consolidation and storage of memory.) And so, E.H. can form no new memories, and his memories of the past are erratic and uncertain; in clinical terms E.H. suffers from partial retrograde amnesia, and total anterograde amnesia. Though he continues to test high on standardized I.Q. tests, and despite his seemingly normal appearance and manner, E.H. is incapable of “remembering” new information for more than seventy seconds; often, it is less than seventy seconds.

      Seventy seconds! A nightmare to contemplate.

      The only consolation, Margot thinks, is that E.H. is a highly congenial person, and seems to thrive upon the attentions of strangers. The nature of his affliction at least precludes mental anguish—(so Margot thinks). His memories of the distant past are sometimes vividly detailed and oneiric; more recent memories (for approximately eighteen months preceding his illness) are likely to be cloudy and indistinct; both have been described as “mildly dissociative”—as if belonging to another person, not E.H. The subject is susceptible to moods, but a very limited range of moods; his affect has flattened, as a caricature is a flattened portrait of the complexity of human personality.

      (Uncannily, E.H. will always recall events out of his past in the same way, using the same vocabulary; but he is never altogether certain if he is remembering correctly, even when external verification confirms that he is remembering correctly.)

      Though E.H. doesn’t consistently remember certain of his relatives (whose faces are altering with time), he can identify the faces of famous people in photographs (if they predate his illness). At times, he demonstrates a remarkable, savant-like memory for recitations: statistics, historical dates, song lyrics, comic-strip characters and film dialogue (he is said to have memorized the entirety of the silent film Potemkin), passages from poems memorized in school (Whitman’s “When Lilacs Last in the Dooryard Bloom’d” is his favorite) and from revered American speeches (Abraham Lincoln’s Gettysburg Address, Franklin Delano Roosevelt’s The Only Thing We Have to Fear Is Fear Itself and Four Freedoms, Martin Luther King, Jr.’s I Have a Dream). He retains curiosity for “news”—watches TV news, each day reads at least two newspapers including the New York Times and the Philadelphia Inquirer—without the ability to remember any of it. Each day he completes the New York Times crossword puzzle as (his family has attested) he’d only occasionally taken time to complete the puzzle before his illness. (“Eli didn’t have that kind of time to waste.”)

      Without seeming to think at all E.H. can recite multiplication tables, solve algebra problems without using a pencil, add up lengthy columns of numbers. It isn’t a surprise to learn that “Elihu Hoopes” had been a successful businessman in a highly competitive field.

      Margot thinks that it is difficult to feel for this healthy-seeming man the visceral pity one might feel for a (visibly) handicapped person, for E.H.’s loss is far more subtle. In fact, though E.H. has been told repeatedly that he has a severe neurological deficit,

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