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Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

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If you regularly see patients with diabetes who experience hypoglycaemia and need expert guidance, then this is the book for you. Hypoglycaemia in Clinical Diabetes, 3rd Edition once again provides health professionals involved in the management of people with diabetes with an expertly written, comprehensive guide to hypoglycaemia, the most common and feared side effect of insulin treatment for diabetes. With reference to ADA and EASD guidelines throughout, topics covered include the physiology of hypoglycaemia and the body’s response to a low blood glucose, its presentation and clinical features, potential morbidity and optimal clinical management in order to achieve and maintain good glycaemic control. Particular attention is paid to the way hypoglycaemia is managed in different groups of patients, such as the elderly, in children, or during pregnancy. New chapters in this edition include: Psychological effects of hypoglycaemia Technology for hypoglycaemia: CSII and CGM Exercise management and hypoglycaemia in type 1 diabetes Neurological sequelae of hypoglycaemia Valuable for diabetologists, endocrinologists, non-specialist physicians and general practitioners, Hypoglycaemia in Clinical Diabetes, 3rd Edition provides expert clinical guidance to this extremely common and potentially serious complication associated with diabetic management.

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Dieser Atlas verbindet als erster die beiden wichtigen Themengebiete der Pädiatrie und Dermatologie. Da sich das Erscheinungsbild von Hauterkrankungen in der Kindheit stark von dem im Erwachsenenalter unterscheiden kann, stellt dieses einzigartige Nachschlagewerk eine wichtige Quelle sowohl für Dermatologen als auch Pädiater dar. Der Schwerpunkt der Diagnostik von Hauterkrankungen beim Kind liegt insbesondere auf der morphologischen Befunderhebung und ihrer lokalisations- und altersabhängigen Manifestation. Ist die exakte klinische Beurteilung und differenzialdiagnostische Abgrenzung erfolgt, kann sie dem Kind häufig invasive Eingriffe zur Diagnosefindung ersparen. Hier setzt der vorliegende Atlas an. Jahrzehntelange klinische Erfahrung der drei Autoren findet in diesem Atlas ihren Ausdruck. Er lebt von seinen Abbildungen, die ihn zu einem einzigartigen Nachschlagewerk machen, das schnell den diagnostischen Blick trainiert und schult. Exzellent und umfangreich bebildert mit genauen Befundbeschreibungen und ausführlichen Differenzialdiagnosen versehen, führt der Atlas schnell von den Hauptmerkmalen, über diagnostische Kriterien, sicher und einfach zur Diagnose und sollte somit in keiner Praxis fehlen.

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An update of a classic student text unlocking the mystery of veterinary neurology and neuroanatomy King's Applied Anatomy of the Central Nervous System of Domestic Mammals, Second Edition is an ideal introduction for those with no prior knowledge of the central nervous system. Presented in a logical and accessible manner, readers can quickly comprehend the essential principles of how the central nervous system is constructed, the way it works and how to recognise damaged components. By blending descriptive anatomy with clinical neurology, the text offers a unique approach – explaining the structure and function of the central nervous system while highlighting the relevance to clinical practice. Revised and updated to cover the latest clinical developments, this second edition includes additional content on electrodiagnostic methods, stem cell transplantation and advanced imaging. The book also comes with a companion website featuring self-assessment questions, label the diagram exercises, and downloadable figures to aid further learning. An excellent introductory text for veterinary students, King's Applied Anatomy of the Central Nervous System of Domestic Mammals, Second Edition is also an invaluable reference for trainee veterinary neurology specialists as well as veterinary practitioners with a particular interest in neurology.

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The most comprehensive evidence-based guide to both obstetrics and gynecology Aimed at practicing obstetricians, gynecologists, and trainees in the specialty, Evidence-based Obstetrics and Gynecology concentrates on the clinical practice areas of diagnosis, investigation and management. The first section of the book discusses evidence-based medicine methodology in the context of the two specialties. The second and third sections cover all the major conditions in obstetrics and gynecology, with each chapter reviewing the best available evidence for management of the particular condition. The chapters are structured in line with EBM methodology, meaning the cases generate the relevant clinical questions. Evidence-based Obstetrics and Gynecology provides in-depth chapter coverage of abnormal vaginal bleeding; ectopic pregnancy; pelvic pain; lower genital tract infections; contraception and sterilization; breast diseases; urogynecology; endocrinology and infertility; puberty and precocious puberty; cervical dysplasia and HPV; cervical, vaginal, vulvar, uterine, and ovarian cancer; preconception care; prenatal care and diagnosis; drugs and medications in pregnancy; maternal complications; chronic hypertension; diabetes mellitus; thyroid disease; neurologic disease; psychiatric disease; postterm pregnancy; fetal complications; preeclampsia; and more. First book to address evidence-based practice for obstetrics and gynecology combined EBM is a highly relevant approach for this high risk specialty Edited by leading US specialist involved in the evidence-based medicine movement Evidence-Based Obstetrics and Gynecology is an important text for obstetricians and gynecologists in practice and in training, as well as for specialist nurses.

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Obstetricians must have a firm grounding in the diagnosis and management of diseases affecting pregnant women as in some cases these may threaten the life of mother or baby or both. This book still remains the standard reference work on medical disorders in obstetric practice in the UK and UK-influenced areas such as the former Commonwealth. Exhaustive in its coverage, it provides clear practical advice on the major medical disorders the obstetrician is likely to encounter. Each chapter reviews the pathophysiology of a complaint then applies the physiological and pathophysiological changes to the problem of diagnosis and management of the disorder as well as giving clear guidance on the welfare of the unborn One of the major strengths of the book is that each chapter teaches the principles of care and gives an appreciation of the natural history of the disease rather than just the facts. Although a scholarly and rigourous account it manages to point out the clinically relevant information that the practising obstetrician will actually need.

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Blackwell's Five-Minute Veterinary Consult: Small Mammal brings together a wide range of information on diseases commonly seen in small exotic mammals into a single, accessible resource. With consistency and broad coverage unparalleled by other texts, this new edition adds sections on chinchillas, guinea pigs, and rodents to the existing rabbit and ferret topics to offer complete coverage of these popular, yet less commonly treated, species. Detailed, up-to-date information on the diagnosis and treatment options for all disorders commonly encountered in exotic companion animals is readily accessible, making this a go-to reference for any veterinarian seeing small exotic mammals, regardless of their experience level with these species. Divided into sections by species, topics are organized alphabetically, with a standardized layout that makes it easy to find information. The Second Edition includes access to customizable Client Education Handouts, which can be downloaded and used in the veterinary clinic, on a companion website at www.wiley.com/go/oglesbee. This book is an essential purchase for general practitioners treating exotic companion animals, exotic animal veterinarians, and veterinary students.

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Encompassing twenty-four clinically important and frequently encountered infectious diseases, the text provides all the necessary background and the most up-to-date treatment of the microbes that cause diseases in humans. Each fully illustrated case study is introduced with a patient history, differential diagnosis, clinical clues, laboratory data, pathogenesis, treatment, and prevention. Presented as unknowns, the cases challenge readers to create a differential diagnosis just as they would in practice, including noninfectious causes that could present similar clinical findings.

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Practical Weight Management in Dogs and Cats is a comprehensive, clinical reference for the veterinary health team, providing the necessary tools to successfully manage pet obesity. Bringing together specialists in nutrition, internal medicine, critical care, and surgery and rehabilitation, the book provides an overview of prevention techniques, clinical management, and practical tips for implementing successful programs and educating owners. Covering topics ranging from taking a nutritional history and body condition scoring to calculating food dosage and client communication tips, this book is a resource for both veterinarians and veterinary technicians to address the growing problem of pet obesity. The book begins by explaining the clinical importance of obesity, then moves on to diagnosing and preventing obesity. The heart of the book is devoted to managing body weight, with chapters on nutritional, pharmacotherapeutic, and exercise strategies, and two unique chapters cover owner compliance and wellness programs. Practical Weight Management in Dogs and Cats offers a collaborative approach to managing weight in pet dogs and cats.

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A timely and topical survey of modern simulation tools and their applications in real-life drug discovery, allowing for better and quicker results in structure-based drug design. The first part of this practical guide for industry professionals describes common tools used in the biomolecular simulation of drugs and their targets. A critical analysis of the accuracy of the predictions, the integration of modeling with other experimental data combined with numerous case studies from different therapeutic fields enable users to quickly adopt these new methods for their current projects. The second part then shows how these tools can be applied to drug discovery and development projects. Modeling experts from the pharmaceutical industry and from leading academic institutions present real-life examples for important target classes such as GPCRs, kinases and amyloids as well as for common challenges in structure-based drug discovery. With its inclusion of novel methods and strategies for the modeling of drug-target interactions in the framework of real-life drug discovery and development, this application-oriented reference is tailor-made for medicinal chemists and those working in the pharmaceutical industry.

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