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This comprehensive reference provides readers with everything they need to know about diagnosing and treating canine and feline respiratory disease. Significantly updated and expanded, it focuses on localization of disease, efficient diagnostic testing, and appropriate therapy. With more images, discussion, and diagrams, this Second Edition includes more detail and new information throughout, particularly in the areas of antimicrobial guidelines, anti-fungal therapies, and ant-viral medications in cats. Logically organized for ease of use in the practice setting, Canine and Feline Respiratory Medicine, Second Edition features problem-based learning to enhance working knowledge of the topics discussed. Chapters cover localization of disease, respiratory diagnostics, respiratory therapeutics, nasal disorders, and diseases of airways. Sections on parenchymal disease; pleural and mediastinal disease; and vascular disorders are also presented.  Offers a complete guide to the diagnosis and treatment of respiratory conditions in canine and feline patients—now expanded to include more detailed and advanced information Focuses on localization of disease, diagnostic testing, and appropriate therapy Thoroughly updated with new antimicrobial guidelines, the latest information on anti-fungal therapy, and new advances in ant-viral medications in cats Includes many new images and topics for discussion Features problem-based learning to support a working understanding of the topics discussed Canine and Feline Respiratory Medicine is an essential resource for veterinary internal medicine specialists, general practitioners, and veterinary students.

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Everything you need to take care of your feline friend   Cats are the purrfect pets: they’re relatively easy to care for, a blast to play with, and sure to win the heart of every member of your family with their loving nature—and sometimes sassy demeanor! Cats For Dummies gives you expert insight into everything from cat behavior to what makes each type of feline unique. With this easy-to-understand guide, you'll be able to tackle those tough cat-astrophes from dealing with problem behaviors like scratching the furniture and missing the litter box—all while learning to understand what your cat is trying to tell you. Happily bring a cat or kitten into your life Keep your new four-legged family member comfortable and safe Live a happy feline-friendly life Keep your cat in prime health Whether you're looking to get your first kitten or adopt a senior cat, this book covers all the basics of feline cat care.

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Praise for the third edition of Bioinformatics “This book is a gem to read and use in practice.” — Briefings in Bioinformatics "This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools." — ChemBioChem “A valuable survey of this fascinating field. . . I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly.” — American Society for Microbiology News “This should be on the bookshelf of every molecular biologist.” — The Quarterly Review of Biology The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today’s biologists are gaining fantastic new insights into the natural world’s most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with. The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forwards. This new edition features:  New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics A thorough treatment of statistical methods as applied to biological data Special topic boxes and appendices highlighting experimental strategies and advanced concepts Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.

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Expert storytellers weave together the science, technological advances, medical urgencies, and human stories that chronicle the development of the field of diagnostic virology. Follows a historical discoveries that defined viruses and their roles in infectious diseases over a century of developments, epidemics, and molecular advances, and continuing into the 21st century with AIDS, HIV, and a future that in no way resembles the past. Features the great names and personalities of diagnostic virology, their contributions, their associations, and their challenges to prove findings that some considered fantasy. Describes how scientists applied revolutionary technologies, studying viruses, first in animal models and tissue culture and progressing to molecular and genetic techniques. Appeals to the pioneer and adventure-seeker who is interested in how a scientific field evolves.

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A guide to the analysis and design of compliant offshore structures that highlights a new generation of platforms Offshore Compliant Platforms provides an authoritative guideto the analysis and design of compliant offshore structures and puts the focus on a new generation of platforms such as: triceratops, Buoyant Leg Storage and Regasification platforms. Whilst the authors – noted experts on the topic – include basic information on the conceptual development of conventional platforms, the book presents detailed descriptions of the design and development of new deep-water platforms. The book describes the preliminary design of triceratops in ultra-deep waters and presents a detailed analysis of environmental loads that are inherent in offshore locations such as wave, wind and current. The new methodology for the dynamic analysis of triceratops under ice loads, predominantly in ice-covered regions, is also examined with detailed parametric studies. In addition, the book covers the structural geometry and the various methods of analysis for assessing the performance of any other similar offshore platform under the special loads. A discussion of the fatigue analysis and service life prediction is also included. This important book: • Includes the analysis and design of compliant offshore structures with a focus on a new generation of platforms • Examines the preliminary design of triceratops in ultra-deep waters • Covers an analysis of environmental loads that are inherent in offshore locations such as wave, wind and current • Reviews the structural geometry and various methods of analysis for assessing the performance of any other similar offshore platform under special loads • Discusses fatigue analysis and service life prediction  Written for engineers and researchers across engineering including civil, mechanical, structural, offshore, ocean and naval architecture, Offshore Compliant Platforms fills the need for a guide to new offshore platforms that provides an understanding of the behaviour of these structures under different loading conditions.

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The Power of Plagues presents a rogues' gallery of epidemic- causing microorganisms placed in the context of world history. Author Irwin W. Sherman introduces the microbes that caused these epidemics and the people who sought (and still seek) to understand how diseases and epidemics are managed. What makes this book especially fascinating are the many threads that Sherman weaves together as he explains how plagues past and present have shaped the outcome of wars and altered the course of medicine, religion, education, feudalism, and science. Cholera gave birth to the field of epidemiology. The bubonic plague epidemic that began in 1346 led to the formation of universities in cities far from the major centers of learning (and hot spots of the Black Death) at that time. And the Anopheles mosquito and malaria aided General George Washington during the American Revolution. Sadly, when microbes have inflicted death and suffering, people have sometimes responded by invoking discrimination, scapegoating, and quarantine, often unfairly, against races or classes of people presumed to be the cause of the epidemic. Pathogens are not the only stars of this book. Many scientists and physicians who toiled to understand, treat, and prevent these plagues are also featured. Sherman tells engaging tales of the development of vaccines, anesthesia, antiseptics, and antibiotics. This arsenal has dramatically reduced the suffering and death caused by infectious diseases, but these plague protectors are imperfect, due to their side effects or attenuation and because microbes almost invariably develop resistance to antimicrobial drugs. The Power of Plagues provides a sobering reminder that plagues are not a thing of the past. Along with the persistence of tuberculosis, malaria, river blindness, and AIDS, emerging and remerging epidemics continue to confound global and national public health efforts. West Nile virus, Lyme disease, and Ebola and Zika viruses are just some of the newest rogues to plague humans. The argument that civilization has been shaped to a significant degree by the power of plagues is compelling, and The Power of Plagues makes the case in an engaging and informative way that will be satisfying to scientists and non-scientists alike.

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Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function.  Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.

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Covers the history of twelve important diseases and addresses public health responses and societal upheavals. Chronicles the ways disease outbreaks shaped traditions and institutions of Western civilization. Explains the effects, causes, and outcomes from past epidemics. Describes a dozen diseases to show how disease control either was achieved or failed. Makes clear the interrelationship between diseases and history. Presents material in a compelling, clear, and jargon-free prose for a wide audience. Provides a picture of the best practices for dealing with disease outbreaks.

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Forgotten People, Forgotten Diseases Second Edition The neglected tropical diseases (NTDs) are the most common infections of the world's poor, but few people know about these diseases and why they are so important. This second edition of Forgotten People, Forgotten Diseases provides an overview of the NTDs and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development. Author Peter J. Hotez highlights a new opportunity to control and perhaps eliminate these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships to create a successful environment for mass drug administration and product development activities. Forgotten People, Forgotten Diseases also Addresses the myriad changes that have occurred in the field since the previous edition. Describes how NTDs have affected impoverished populations for centuries, changing world history. Considers the future impact of alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases is an essential resource for anyone seeking a roadmap to coordinate global advocacy and mobilization of resources to combat NTDs.

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The popular introduction to the genomic revolution for non-scientists—the revised and updated new edition Welcome to the Genome  is an accessible, up-to-date introduction to genomics—the interdisciplinary field of biology focused on the structure, function, evolution, mapping, and editing of an organism's complete set of DNA. Written for non-experts, this user-friendly book explains how genomes are sequenced and explores the discoveries and challenges of this revolutionary technology. Genomics is a mixture of many fields, including not only biology, engineering, computer science, and mathematics, but also social sciences and humanities. This unique guide addresses both the science of genomics and the ethical, moral, and social questions that rise from the technology. There have been many exciting developments in genomics since this book's first publication. Accordingly, the second edition of  Welcome to the Genome  offers substantial new and updated content to reflect recent major advances in genome-level sequencing and analysis, and demonstrates the vast increase in biological knowledge over the past decade. New sections cover next-generation technologies such as Illumina and PacBio sequencing, while expanded chapters discuss controversial ethical and philosophical issues raised by genomic technology, such as direct-to-consumer genetic testing. An essential resource for understanding the still-evolving genomic revolution, this book: Introduces non-scientists to basic molecular principles and illustrates how they are shaping the genomic revolution in medicine, biology, and conservation biology Explores a wide range of topics within the field such as genetic diversity, genome structure, genetic cloning, forensic genetics, and more Includes full-color illustrations and topical examples Presents material in an accessible, user-friendly style, requiring no expertise in genomics Discusses past discoveries, current research, and future possibilities in the field Sponsored by the American Museum of Natural History,  Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future  is a must-read book for anyone interested in the scientific foundation for understanding the development and evolutionary heritage of all life.

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